270 citations
,
March 2012 in “Dermatologic Surgery” This study found that autologous platelet-rich plasma increased hair growth potential by enhancing dermal papilla cell proliferation and stimulating key signaling pathways in both cell cultures and mice models.
58 citations
,
January 2020 in “International Journal of Molecular Sciences” This review evaluates various kits for isolating platelet-rich plasma using established processing standards and finds they enable compliance with consensus quality criteria; ongoing research is needed to refine these procedures for improved consistency and safety.
44 citations
,
May 2022 in “Journal of Assisted Reproduction and Genetics”
42 citations
,
May 2016 in “American Journal of Clinical Dermatology” This review discusses the use of platelet-rich plasma for pattern hair loss treatment and examines existing clinical studies without presenting new clinical results.
39 citations
,
January 2021 in “BioMed Research International” This review explores the variability in platelet-rich plasma therapy outcomes across different medical applications, attributing disparities to inconsistent blood processing methods, and it reports no new clinical results.
37 citations
,
March 2009 in “Hair transplant forum international” This small study observed that infusing platelet rich plasma into the scalp reversed hair miniaturization and stimulated new hair growth in patients with androgenetic alopecia and alopecia areata over 8 months.
31 citations
,
March 2020 in “International Journal of Regenerative Medicine” This study found that intraovarian PRP treatment in women with low ovarian reserve was associated with significant increases in serum AMH levels in some patients, typically within four weeks.
19 citations
,
January 2010 in “Hair transplant forum international” This abstract describes the components found in the alpha and dense granules of platelets, but it provides no new research findings.
18 citations
,
August 2019 in “Journal of Cosmetic Dermatology” This study found that autologous platelet-rich plasma was associated with increased hair density in people with pattern hair loss, but with considerable variability and unclear risks of bias.
14 citations
,
April 2019 in “The Ukrainian Biochemical Journal” This study developed a simple method to prepare highly concentrated, resting platelet-rich plasma suitable for cell therapy, effectively preventing clotting while maintaining platelet reactivity and minimizing hemorrhage risk.
13 citations
,
July 2012 in “Dermatologic Surgery” Platelet-rich plasma (PRP) may help promote hair growth and improve graft survival after hair transplantation, but more research is needed to confirm its effectiveness and determine the best dosage.
5 citations
,
January 2019 in “Revista Latino-americana De Enfermagem” In this study, the direct cost of producing autologous platelet rich plasma gel in a Rio de Janeiro university hospital was found to be US $4.88 per session, highlighting its potential as a low-cost and accessible treatment option within the Unified Health System.
4 citations
,
January 2015 in “Journal of clinical & experimental dermatology research” This study observed a slight improvement in hair density in men with androgenetic alopecia treated with autologous platelet rich plasma, but only two cases showed cosmetic improvement.
4 citations
,
March 2008 in “Hair transplant forum international” This abstract provides an overview of the importance of using reliable and valid information for evidence-based medicine, without presenting new experimental results.
3 citations
,
February 2021 in “Medical journal, Armed Forces India” In this observational study, the combination of PRP and 5% minoxidil was more effective than minoxidil alone in promoting hair growth in men with androgenetic alopecia.
3 citations
,
November 2016 in “Journal of Pakistan Association of Dermatology” This study found that autologous platelet rich plasma (PRP) may be a safe and effective treatment for limited alopecia areata, with varying levels of hair regrowth observed among patients.
3 citations
,
October 2020 in “Journal of Transfusion Medicine” This review discusses the use and mechanisms of platelet-rich plasma therapy and highlights the need for standardized preparation and application protocols, without reporting new clinical results.
2 citations
,
April 2024 in “International Wound Journal” Combining UV therapy with PRP heals chronic wounds faster and reduces pain.
2 citations
,
February 2013 in “Journal of The American Academy of Dermatology” This study found that the cross-section trichometer (HairCheck device) can accurately and sensitively measure hair mass index changes, offering a convenient tool for assessing hair density and diameter in patients with alopecia.
1 citations
,
July 2018 in “Journal of Pakistan Association of Dermatology” This randomized prospective study found that microneedling combined with autologous platelet-rich plasma resulted in significant hair regrowth and reduction in SALT score after 12 weeks in patients with chronic and stable alopecia areata, suggesting it as a safe and efficient treatment option.
1 citations
,
January 2018 in “Journal of V. N. Karazin Kharkiv National University: Series Medicine” This review analyzes studies on autologous platelet-rich plasma for androgenic alopecia, reporting mixed results and highlighting the need for standardized protocols and further research.
March 2026 in “Frontiers in Pharmacology” The study concluded that the Exprecell™ device for preparing anticoagulant-free f-PRF increases volume yield and simplifies the process while maintaining biological activity comparable to conventional methods, suggesting potential clinical utility.
This review synthesizes existing research on autologous platelet-rich plasma for treating androgenetic alopecia, suggesting its promise with standardized protocols and personalized approaches, but reports no new clinical results.
July 2025 in “Clinical Cosmetic and Investigational Dermatology” This study found that platelet-rich plasma therapy significantly improved hair density and reduced hair shedding in Vietnamese patients with androgenetic alopecia, with high patient satisfaction and minimal side effects.
May 2025 in “Medicine and ecology” This literature review highlights the widespread use of platelet-rich plasma in medicine but notes inconclusive evidence for its clinical efficacy due to specimen variability and unresolved methodological issues.
February 2025 in “Journal of Pharmacy And Bioallied Sciences” In this study, researchers found that autologous platelet-rich plasma injections significantly improved hair density and patient satisfaction in both male and female patients with androgenetic alopecia, with no major side effects reported.
December 2024 in “Journal of The Society of Obstetricians and Gynaecologists of Pakistan” This study found that injecting autologous PRP significantly reduced the healing time of superficial wound dehiscence after Pfannenstiel incision surgery to an average of 15.80 days, compared to 20.30 days for conventional wound care alone.
July 2024 in “Anais Brasileiros de Dermatologia” PRP injections can increase hair density in people with androgenic alopecia.
This study concluded that monthly intralesional autologous platelet-rich plasma therapy significantly decreased alopecia areata severity over four months compared to daily 5% topical minoxidil therapy.
January 2024 in “Advances in Dermatology and Allergology” This abstract highlights the prevalence of androgenetic alopecia in men and young adults and mentions the psychological impact, noting that while various therapies exist, clear treatment algorithms are lacking according to this source.