Discussion of Field Effects After Intraovarian Injection of Autologous Platelet-Rich Plasma
April 2023
in “
Bulletin of the National Research Centre
”
TLDR The document concludes that more research is needed to understand how PRP affects the ovaries and to standardize its use in treatment.
The document discusses the potential of autologous platelet-rich plasma (PRP) as an alternative treatment to improve ovarian reserve in pre-menopausal women. It suggests that intraovarian PRP may interact not only with follicles or oocyte precursors but also with other ovarian components like stroma, perivascular cells, immune cells, granulosa cells, and endothelium that respond to platelet cytokines. The study indicates that PRP could influence the ovarian microclimate, potentially affecting follicle assembly and oocyte competency. However, the document concludes that further research is needed to understand the specific ovarian stromal responses following PRP and calls for standardization in PRP processing techniques and injection methods to increase its clinical use.
