Becker Nevus of the Face with Asymmetrical Growth of Beard Hair

February 2013 in “ Journal of the American Academy of Dermatology ”

alopecia areata epidermal growth factor epidermal growth factor receptor EGF EGFR autologous platelet-rich plasma androgenetic alopecia Becker's nevus androgen metabolism cross-section trichometry AA PRP BN CST

TLDR Certain gene variations may increase the risk of alopecia, and platelet-rich plasma treatment can improve hair density in those with hair loss; a rare case of facial Becker's nevus was linked to uneven beard growth.

The document reports on various studies related to hair growth and alopecia. One study, involving 231 alopecia areata (AA) patients and 270 healthy controls, found significant associations between certain epidermal growth factor (EGF) and epidermal growth factor receptor (EGFR) gene polymorphisms and susceptibility to AA in the Korean population. It also noted that specific EGF and EGFR polymorphisms were linked to nail involvement and body hair loss in AA patients. Another study evaluated the effectiveness of autologous platelet-rich plasma (PRP) mesotherapy in 31 patients with androgenetic alopecia compared to 31 controls. After 12 months, the PRP-treated group showed statistically higher hair density and a borderline increase in hair number. Additionally, a unique case of Becker's nevus (BN) on the face of a 14-year-old girl with asymmetrical beard hair growth was described, questioning the relationship between BN and androgen metabolism. Lastly, a study introduced cross-section trichometry (CST) as a tool for assessing alopecia progression and treatment response, demonstrating its ability to measure changes in hair density and diameter accurately.

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