Comparison of Clinical Efficacy and Trichoscopic Changes in Scalp Alopecia Areata Following Treatment with Intralesional Triamcinolone Acetonide and Autologous Platelet-Rich Plasma
July 2023
in “
Clinical dermatology review
”
Studysummary This study found that intralesional triamcinolone acetonide is more effective and faster than platelet-rich plasma in promoting hair regrowth for scalp alopecia areata.
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The research compared the effectiveness of intralesional triamcinolone acetonide and autologous platelet-rich plasma (PRP) in treating scalp alopecia areata (AA) in 32 patients. The results indicated that intralesional triamcinolone acetonide was more effective, with 75% of patients showing regrowth of terminal hair in clusters and 25% showing complete hair regrowth after 12 weeks. In contrast, among PRP-treated patients, 50% had sparse pigmented hair regrowth, 40.6% showed terminal hair regrowth in clusters, and only 9.4% had complete hair regrowth. Hair growth was also observed earlier in triamcinolone-treated patches. No adverse effects or recurrences were reported in either treatment group. The study concluded that intralesional triamcinolone acetonide is a superior treatment for AA than intralesional autologous PRP due to its faster hair growth and higher rate of complete hair regrowth.
