Search

for
Search:

Sort by

Research

30-60 / 66 results

In Vitro Antibacterial and Antioxidant Activities, Pharmacokinetics, and In Silico Molecular Docking Study of Phytochemicals from the Roots of Ziziphus Spina-Christi

research In Vitro Antibacterial and Antioxidant Activities, Pharmacokinetics, and In Silico Molecular Docking Study of Phytochemicals from the Roots of Ziziphus Spina-Christi

January 2024 in “Biochemistry Research International”

Compounds from Ziziphus spina-christi roots show strong antibacterial and antioxidant potential.

research Bioactive Metabolites of Edible Mushrooms Efficacious Against Androgenic Alopecia: Targeting SRD5A2 Using Computational Approach

March 2022 in “Research Square (Research Square)”

Mushroom compounds may help treat hair loss better than Finasteride.

research New Target for Minoxidil in the Treatment of Androgenetic Alopecia

August 2023 in “Drug Design Development and Therapy”

Minoxidil may work for hair loss by reducing androgen sensitivity and altering hormone-related enzymes.

research In Silico Study of 12 Phytosterol Compounds in Moringa (Moringa Oleifera Lamk.) Seed Oil on 5α-Reductase Enzyme Inhibition Activity as Anti-Alopecia

November 2022 in “International Journal of Applied Pharmaceutics”

Ergostadienol from Moringa seed oil may help prevent hair loss.

research Targeting Smoothened for Therapeutic Gain

105 citations, April 2014 in “Trends in Pharmacological Sciences”

Targeting the Smoothened receptor shows promise for treating certain cancers.

research Triclocarban, Triclosan, Bromochlorophene, Chlorophene, and Climbazole Effects on Nuclear Receptors: An In Silico and In Vitro Study

29 citations, October 2020 in “Environmental health perspectives”

Five preservatives may disrupt hormone function and need more health and environmental risk assessment.

research Class III Peroxidases PRX01, PRX44, and PRX73 Control Root Hair Growth in Arabidopsis Thaliana

19 citations, May 2022 in “International journal of molecular sciences”

PRX01, PRX44, and PRX73 are essential for root hair growth in Arabidopsis thaliana.

Identification of Drug-Disease Associations Using Information of Molecular Structures and Clinical Symptoms via Deep Convolutional Neural Network

research Identification of Drug-Disease Associations Using Information of Molecular Structures and Clinical Symptoms via Deep Convolutional Neural Network

18 citations, January 2020 in “Frontiers in Chemistry”

A new model can predict drug-disease links well, helping drug research.

research Homology Modeling of 5-Alpha-Reductase 2 Using Available Experimental Data

5 citations, January 2018 in “Interdisciplinary sciences: computational life sciences”

Accurate protein modeling can help develop new treatments for prostate cancer and other diseases.

Active Anti-Alopecia Chemical Identification of Merremia Peltata Leaves and Computational Study Toward Androgen Receptor Using Molecular Docking and Molecular Dynamic Simulation

research Active Anti-Alopecia Chemical Identification of Merremia Peltata Leaves and Computational Study Toward Androgen Receptor Using Molecular Docking and Molecular Dynamic Simulation

4 citations, August 2022 in “The Scientific World Journal”

Merremia peltata leaf extract, particularly the bufotalinin compound, shows potential for treating hair loss.

research Identification of Beta-Sitosterol and Stigmasterol as Possible Inhibitors of 5 Alpha-Reductase 1: An In-Silico Study

3 citations, January 2022 in “Precision medicine and clinical omics”

Beta-sitosterol and stigmasterol might help prevent hair loss by blocking a specific enzyme.

research Ficus Benghalensis as Potential Inhibitor of 5α-Reductase for Hair Growth Promotion: In Vitro, In Silico, and In Vivo Evaluation

3 citations, December 2021 in “Frontiers in Pharmacology”

Ficus benghalensis leaf extracts can effectively promote hair growth and inhibit hair loss.

research In Silico Structural Prediction of Human Steroid 5α-Reductase Type II

3 citations, March 2016 in “Medicinal Chemistry Research”

Scientists found out the structure of a human enzyme linked to prostate cancer and hair loss, which could help in designing drugs.

Anti-Alopecia Activity of Coumarin Derivatives from Merremia Peltata Leaves and Their Binding to Androgen Receptors: A Molecular Study

research Anti-Alopecia Activity of Coumarin Derivatives from Merremia Peltata Leaves and Their Binding to Androgen Receptors: A Molecular Study

2 citations, April 2023 in “Pharmaceuticals”

Scopolin and scopoletin from Merremia peltata leaves may help treat hair loss and showed promising results in rabbit tests.

research 4-Octyl Itaconate Alleviates Cisplatin-Induced Ferroptosis Possibly Via Activating the NRF2/HO-1 Signalling Pathway

1 citations, March 2024 in “Journal of Cellular and Molecular Medicine”

4-octyl itaconate may prevent hearing loss caused by the drug cisplatin by activating certain cell protection pathways.

Logic-Based Modeling and Drug Repurposing for the Prediction of Novel Therapeutic Targets and Combination Regimens Against E2F1-Driven Melanoma Progression

research Logic-Based Modeling and Drug Repurposing for the Prediction of Novel Therapeutic Targets and Combination Regimens Against E2F1-Driven Melanoma Progression

1 citations, November 2023 in “BMC chemistry”

Tadalafil and Finasteride may help treat aggressive melanoma.

Anti-Alopecia Activity of Alkaloids from Noni Fruit Against Dihydrotestosterone-Induced Male Rabbits and Its Molecular Mechanism: In Vivo and In Silico Studies

research Anti-Alopecia Activity of Alkaloids from Noni Fruit Against Dihydrotestosterone-Induced Male Rabbits and Its Molecular Mechanism: In Vivo and In Silico Studies

1 citations, December 2022 in “Pharmaceuticals”

Noni fruit extract, specifically the FEA-3 sub-fraction, can increase hair growth and reduce baldness in male rabbits, potentially acting like common hair loss treatments.

research Exploring the Mechanisms and Molecular Targets of Taohong Siwu Decoction for the Treatment of Androgenetic Alopecia Based on Network Analysis and Molecular Docking

1 citations, July 2022 in “Clinical, Cosmetic and Investigational Dermatology”

Taohong Siwu Decoction may help treat hair loss by targeting multiple genes and pathways.

Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4+ T Cell Activities via Direct Binding With Cytochrome P450 1B1

research Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4+ T Cell Activities via Direct Binding With Cytochrome P450 1B1

1 citations, May 2022 in “Frontiers in Pharmacology”

Astilbin can potentially calm overactive immune responses, like in Type 1 Diabetes, by suppressing certain cell activities and reducing inflammation.

research Isolation and Identification of Hair Growth Potential Fraction from Active Plant Extract of Blumea Eriantha DC Grown in Western Ghat of India: In Silico Study

1 citations, April 2022 in “Journal of Ayurveda and integrative medicine”

Blumea eriantha DC extract shows strong potential for promoting hair growth.

research Network Pharmacology Reveals Curcuma Aeruginosa Roxb. Regulates MAPK and HIF-1 Pathways to Treat Androgenetic Alopecia

July 2024 in “Biology”

Curcuma aeruginosa Roxb. may help treat hair loss by affecting specific biological pathways.

research Antifungal Activity and Hair Growth Stimulation of Purple Sweet Potato Leaf Fraction (Ipomoea Batatas) and Its Molecular Mechanism Through Androgen Receptor Inhibition

May 2024 in “Pharmacia/Farmaciâ”

Purple sweet potato leaf extracts can help treat hair loss and fungal infections.

research Bioprospecting of Potential Inhibitors of 5alpha Reductase 2 from Relevant Ethno-Pharmacological Plants via In Silico Techniques

May 2024 in “Scientific African”

Three natural compounds from Ghanaian plants may help treat BPH and alopecia.

research Discovery Of A Novel And Highly Selective JAK3 Inhibitor As A Potent Hair Growth Promoter

April 2024 in “Journal of translational medicine”

MJ04, a new compound, effectively promotes hair growth and is a potential topical treatment for hair loss.

research Melatonin's Effect on Hair Follicles in a Goat (Capra Hircus) Animal Model

April 2024 in “Frontiers in endocrinology (Lausanne)”

Melatonin improved secondary hair growth in goats but didn't affect primary hair density or litter size.

research Identification of Potential Cytochrome P450c 17 Alpha Inhibitors for the Treatment of PCOS via Scaffold Hopping and Fragment-Based De-Novo Drug Design

February 2024

Potential new drugs for treating PCOS were identified.

research Adsorption of Diclofenac and PFBS on a Hair Keratin Dimer

December 2023 in “The journal of physical chemistry. B (1997 : Online)”

Human hair keratin might be good for filtering out harmful substances from water.

Virtual Insights into Natural Compounds as Potential 5α-Reductase Type II Inhibitors: A Structure-Based Screening and Molecular Dynamics Simulation Study

research Virtual Insights into Natural Compounds as Potential 5α-Reductase Type II Inhibitors: A Structure-Based Screening and Molecular Dynamics Simulation Study

November 2023 in “Life”

Eriocitrin and silymarin might be effective for hair loss treatment and need more research.

Promotion of Hair Regrowth in Androgenetic Alopecia with Supplemented Erzhi Wan: Exploring Its Mechanism Using Network Pharmacology and Molecular Docking

research Promotion of Hair Regrowth in Androgenetic Alopecia with Supplemented Erzhi Wan: Exploring Its Mechanism Using Network Pharmacology and Molecular Docking

October 2023 in “Clinical, Cosmetic and Investigational Dermatology”

Supplemented Erzhi Wan may help regrow hair in male pattern baldness by affecting certain cell signaling pathways.

research The Medicinal Activity of Lyophilized Aqueous Seed Extract of Lepidium Sativum L. in an Androgenic Alopecia Model

May 2023 in “Scientific Reports”

The seed extract of Lepidium sativum L. can potentially treat hair loss, showing effects similar to 5% minoxidil.

← Previous page Next page →