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In this study, finasteride-treated WAG/Rij rats showed a significant increase in spike-wave discharges when administered endogenous steroids THPROG and THDOC, indicating potential exacerbation of absence seizures.

This study found that sulfated CCK octapeptide reduces psoriasis-like skin inflammation in mice, suggesting a new pathophysiological role for CCK in regulating epidermal inflammation.

Milk-derived vesicles are promising for delivering drugs orally and treating various conditions.

This study found that hMSC secretomes from umbilical cord Wharton's jelly had the most potent angiogenic effects, whereas those from adipose tissue demonstrated the weakest angiogenic potential.

This study found that Musashi-2 regulates mRNA targets to restrict epithelial cell migration, revealing a key function of Msi2 beyond its known role in promoting cell growth.

In this study, the combination of Serenoa repens extract with Phenolmicin P3 and Bosexil suppositories significantly improved lower urinary tract symptoms and decreased PSA levels in patients with benign prostatic obstruction-related symptoms.

This study found that in rodent models, the ability of D1 dopamine receptor activation to impair sensory gating is facilitated by 5α-reductase type 1, which produces allopregnanolone.

This study suggests that oleosomes in Sesbania nodules are utilized for cell growth and development but are not directly involved in nitrogen fixation.

This study found that normal human epidermis expresses TSH and may be an indirect target of TSH signaling, with expression regulated by endocrine controls of the hypothalamic-pituitary-thyroid axis.

This study found that mesenchymal stem cell-derived exosomes reduced hearing and hair cell loss caused by neomycin in experimental models by modulating autophagy, which promoted cell survival and lowered oxidative stress and apoptosis, indicating potential for deafness treatment.

This study found that testosterone enhances glucose-stimulated insulin secretion in male and female human islets through its conversion to DHT and E2, a process disrupted by 5α-reductase and aromatase inhibitors.

This study found that castration increased 5 alpha-reductase activity in the sebaceous glands of male hamsters, but administering testosterone propionate or 5 alpha-dihydrotestosterone inhibited this effect.

This study found that oral contraceptives effectively suppressed hyperandrogenemia in most patients with hyperandrogenic-insulin-resistant acanthosis nigricans syndrome, though GnRH-a therapy was beneficial for those not responding initially.

In this study, the vitamin D analogues 1 alpha,25-dihydroxy-vitamin D3 and calcipotriol were found to thin the living cell layer and affect differentiation marker expression in organotypic cultures of human outer root sheath cells.

This study found that Agaricus bisporus-derived β-Glucan particles showed potential as an anticancer, antimicrobial, and antioxidant agent, inducing apoptosis and disrupting mitochondrial membrane potential in cervical cancer HeLa cells.

This study found that treatment with vitamin D increased the expression of LL-37 through the vitamin D receptor in cultured sebocytes.

This study found that Secretory Phospholipase A2-IIA (sPLA2-IIA) promotes proliferation through JNK/c-Jun signaling, distinctively affecting normal stem cells and cancer cells, suggesting it as a potential target for cancer treatment.

This review discusses regenerative therapy approaches, such as tissue stem cell transplantation and gene therapy, for restoring salivary gland function in xerostomia and reports no new research results.

Hair follicles are crucial for maintaining skin barrier function.

This study found that phosphodiesterase inhibitors may suppress the proliferation of benign prostatic hyperplasia epithelial cells by modulating CCL5 levels in low androgen conditions.

This study suggests that a topical hydroalcoholic extract of liquorice root significantly reduced sebaceous gland size in Syrian hamsters, indicating potential for use in anti-acne therapy.

This article discusses the structure and function of sebaceous glands and their role in skin moisture but reports no new research findings.

In this study, Iris germanica L. rhizome-derived exosomes were found to reduce oxidative stress, enhance antioxidant enzyme transcription, and restore cellular function in human epidermal keratinocytes, suggesting potential protective effects against oxidative-stress-induced skin damage.

This chapter reviews the male accessory sex glands in rats and their responses to hormonal influences, detailing common spontaneous changes and effects of compounds, but it provides no new experimental findings.

This study found that acid regulation of the TRPV3 channel can inhibit its function from outside the cell while facilitating it from inside, providing insights into skin barrier and disorder mechanisms related to tissue acidosis.

This study found that hamster sebaceous glands have high affinity binding sites for dihydrotestosterone, with competition from other steroids indicating specific binding characteristics.

This review discusses ongoing and past trials for novel acne treatments, focusing on topical agents with potential sebosuppressive, antimicrobial, or anti-inflammatory effects, without reporting new clinical results.

This review examines regulatory mechanisms of quiescent stem cells in tissue homeostasis, drawing on observations from the intestine and other self-renewing tissues, without presenting new data.

This paper reviews the properties, characteristics, and applications of deep eutectic solvents as environmentally friendly alternatives for extracting bioactive compounds from natural sources in the pharmaceutical industry.

In this study, researchers found that exosomes derived from Pinctada martensii mucus can effectively inhibit melanin production in melanoma cells and zebrafish without adverse effects, potentially offering a promising therapeutic strategy for treating pigmentary disorders by modulating the NF-κB signaling pathway.