Male Accessory Sex Glands
November 2017
in “
Elsevier eBooks
”
TLDR Male accessory sex glands in rats rarely develop tumors and respond to hormones.
The male accessory sex glands, originating from the mesonephric duct and urogenital sinus, were responsive to androgens like dihydrotestosterone, making them useful indicators of hormonal influences. In rats, neoplasms in these glands were rare among commonly used strains in toxicologic assessments, though some strains served as models for human diseases. The chapter detailed spontaneous nonneoplastic and neoplastic changes in these glands and their responses to various compounds.