8 citations,
January 1986 in “Journal of hepatology” Men with liver cancer have higher levels of a specific testosterone byproduct in their liver and blood, despite overall lower male hormone levels.
7 citations,
January 2016 in “Laboratory Investigation” TR3 is mainly found in hair follicle stem cells and may be involved in hair loss.
7 citations,
January 2003 in “Elsevier eBooks” Testosterone is crucial for development, growth, and various body functions in mammals.
7 citations,
January 1994 in “Annual Reports in Medicinal Chemistry” Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.
6 citations,
May 2022 in “Research and reports in urology” Caesalpinia bonduc seed extracts may help treat enlarged prostate in rats.
6 citations,
November 2020 in “Molecular and Cellular Endocrinology” Androgens reduce BMP2, which weakens the ability of certain cells to help hair stem cells become different types of cells.
5 citations,
January 2005 in “Journal of Enzyme Inhibition and Medicinal Chemistry” New steroids were effective in blocking male hormone receptors in hamster prostates.
5 citations,
July 2000 in “Southern Medical Journal” Male pattern baldness is often genetic and linked to a hormone, with treatments like finasteride and minoxidil being effective for some men.
4 citations,
July 2021 in “Journal of Dermatological Treatment” Finasteride helps hair growth but may cause sexual side effects and depression.
4 citations,
September 2020 in “Frontiers in Microbiology” Algal oligosaccharides help prevent hair loss and promote hair growth.
3 citations,
June 2021 in “Cosmetics” A mix of sulforaphane, L-menthol, and dexpanthenol could help increase hair growth and reduce hair loss.
3 citations,
October 2019 in “Dermatologic Therapy” Hair loss in men is mainly caused by hormones and genes, and while current treatments can slow it down, they can't fully stop it.
2 citations,
February 2021 in “Brain Research” Testosterone affects blood pressure control and inflammation in male rats with endotoxic shock, and blocking certain hormones may help treat it.
2 citations,
November 2017 in “Elsevier eBooks” Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.
2 citations,
November 2017 in “Biotechnology Letters” Researchers found four natural compounds that can change DHT levels in prostate cancer cells.
2 citations,
October 1998 in “Family Practice” New oral treatment, finasteride, effectively and safely treats common hair loss.
1 citations,
October 2023 in “International journal of Ayurveda and pharma research” Herbal medications might be safer and more effective for hair loss than synthetic treatments.
1 citations,
August 2020 in “Food Research” Plant extracts like Avicennia marina, Boehmeria nipononivea, and Camellia sinensis could potentially treat hair loss with fewer side effects than synthetic drugs.
1 citations,
May 2018 in “Clinical chemistry” The girl's unexpected pubic hair growth led to a diagnosis different from complete androgen insensitivity syndrome.
1 citations,
October 2017 in “Elsevier eBooks” Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.
Minoxidil helps stimulate hair growth and enlarge small follicles in common hair loss, but doesn't stop it, and its effects can be boosted when combined with finasteride.
1 citations,
June 2012 in “Springer eBooks” Acupuncture may improve reproductive and metabolic functions in PCOS without negative side effects, but more research is needed to confirm its effectiveness.
1 citations,
January 2011 The document concludes that androgenetic alopecia is common, has a genetic link, and can be diagnosed and treated with medications like finasteride and minoxidil.
November 2023 in “Scientific reports” The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.
May 2021 in “Journal of Advances in Internal Medicine” A 13-year-old with 46 XY DSD had ambiguous genitalia due to incomplete masculinization.
April 2019 in “Journal of Investigative Dermatology” Testosterone affects androgen receptors and lipid storage in cells, while DHEA does not convert to testosterone or affect these receptors in the same way.
January 2019 in “Oncogen” Triple Hormonal Blockade (ADT3) can effectively manage prostate cancer but requires careful monitoring for heart risks.
Changes in skin bacteria can affect hair loss and new treatments targeting these bacteria may prevent balding without sexual side effects.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Androgens increase growth factors in skin cells, which may lead to acne.
Female hair loss is often hereditary and can be treated with medication, hair transplants, and lasers.