Sulforaphane, L-Menthol, and Dexpanthenol as a Novel Active Cosmetic Ingredient Composition for Relieving Hair Loss Symptoms

    June 2021 in “ Cosmetics ”
    Youngkum Park, Kanghyun Choi, Hyoseon Kim … Junehyun Kim
    Studysummary This study found that sulforaphane may help alleviate hair loss by increasing hair count after 18 weeks of use and enhancing the expression of a DHT-degrading enzyme in cellular models.
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    Research cited in this study 14

    1. A Mixture of Tocopherol Acetate and L-Menthol Synergistically Promotes Hair Growth in C57BL/6 Mice Pharmaceutics · 2020
    2. Protective Role of Nutritional Plants Containing Flavonoids in Hair Follicle Disruption: A Review International Journal of Molecular Sciences · 2020
    3. Parietal Scalp Is Another Affected Area in Female Pattern Hair Loss: An Analysis of Hair Density and Hair Diameter Clinical, Cosmetic and Investigational Dermatology · 2017
    4. Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men – Short Version Journal of The European Academy of Dermatology and Venereology · 2017
    5. A Review of the Use of Biotin for Hair Loss Skin appendage disorders · 2017
    6. Oral Ruxolitinib Induces Hair Regrowth in Patients with Moderate-to-Severe Alopecia Areata JCI insight · 2016
    7. Androgenetic Alopecia: An Update Of Treatment Options Drugs · 2016
    8. Sulforaphane Promotes Murine Hair Growth by Accelerating the Degradation of Dihydrotestosterone Biochemical and Biophysical Research Communications · 2016
    9. Androgenetic Alopecia: An Evidence-Based Treatment Update American Journal of Clinical Dermatology · 2014
    10. The Efficacy and Safety of 5α-Reductase Inhibitors in Androgenetic Alopecia: A Network Meta-Analysis and Benefit–Risk Assessment of Finasteride and Dutasteride Journal of Dermatological Treatment · 2013
    11. Molecular Principles of Hair Follicle Induction and Morphogenesis BioEssays · 2005
    12. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
    13. Male Androgenetic Alopecia Clinical and Experimental Dermatology · 2002
    14. Finasteride in the Treatment of Men with Androgenetic Alopecia Journal of The American Academy of Dermatology · 1998