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Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.

The document concludes that hair transplantation and gene therapy may be important for future hair loss treatment.

Beard and scalp hair cells have different gene expressions, which may affect beard growth characteristics.

DKK-1 gene linked to hair loss in AGA and AA patients; more research needed for potential therapy.

Nanotechnology is improving drug delivery and targeting, with promising applications in cancer treatment, gene therapy, and cosmetics, but challenges remain in ensuring precise delivery and safety.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

Dihydrotestosterone changes some hormone-related gene expressions in rat pituitary glands but doesn't affect the estrous cycle.

Platelet-rich plasma can potentially improve hair regeneration by increasing follicular gene expression and hair growth activity.

Chronic stress in mice changes skin metabolism and gene expression, leading to hair loss.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.

The lncRNA LOXL1-AS1 may help diagnose and treat androgenic alopecia.

Metformin is less effective in men with early-onset hair loss.

Common latent viruses might contribute to male-pattern baldness by disrupting cell processes that normally suppress hair loss-related proteins.

Shorter CAG repeats may cause hair and skin issues, while longer ones may link to acne.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.

Vitamin C derivative increases versican in cells, potentially aiding hair growth.

PSA levels could help detect illegal steroid use in female athletes but face challenges like cost and PCOS prevalence.

Testosterone can both promote hair growth and cause baldness by affecting hair growth signals.

TRPV3 could be a target for treating pain, skin disorders, and hair problems, but more research is needed to create effective drugs.

Versican, a protein, is less present in thinning hair follicles and this decrease might contribute to common hair loss in men.

Hair follicles in people with alopecia have lower levels of a key blood vessel growth protein.

New compounds with carborane showed anti-androgen effects similar to flutamide.

The VEGF +405G allele may increase the risk of PCOS in South Indian women.

Platelet-Rich Plasma therapy significantly increases hair density in people with Androgenic Alopecia, and works better with more treatments per month and in younger patients.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

Certain changes in the VEGF gene can increase or decrease the risk of polycystic ovary syndrome.

PCOS has a strong genetic basis, but more research is needed to fully understand it.