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Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Rice bran mineral extract may help promote hair growth and prevent hair loss.

Higher levels of the DP2 receptor may lead to hair loss.

Tofacitinib helps mice grow more hair by increasing noggin and BMP4 levels, possibly better than minoxidil.

Changing protein kinase levels in pituitary cells affects calcium flow and beta-endorphin release.

Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.

Low-level laser treatment helps mice grow hair by increasing certain protein levels linked to hair growth.

Melatonin applied to the scalp helps increase hair density in people with early hair loss.

Prolactin affects hair growth cycles and can cause early hair follicle regression.

Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

Nanog gene boosts stem cells, helps hair growth, and may treat hair loss.

The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

The Hairless gene is crucial for hair cell development, affecting whether skin cells become hair or skin and oil gland cells.

E211 G>A gene linked to lower risk of severe prostate cancer and hair loss.

The document concludes that hair transplantation and gene therapy may be important for future hair loss treatment.

The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.

Nanotechnology is improving drug delivery and targeting, with promising applications in cancer treatment, gene therapy, and cosmetics, but challenges remain in ensuring precise delivery and safety.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

A person with a specific gene mutation had extra teeth, unique jaw and hair features not seen before in this condition.

Pattern baldness is likely caused by a dominant gene influenced by testosterone levels, making it more common in men.

Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.

Inhibiting Zyxin may help treat androgenetic alopecia by promoting hair growth.

Furless male rabbits grew slightly faster and heavier than furred ones, but testosterone levels were not the cause.

The document concludes that dermal papilla cells are key for hair growth and could be used in new hair loss treatments.

The engineered yeast strain BLYAS can quickly and sensitively detect androgenic chemicals.

The VEGF +405G allele may increase the risk of PCOS in South Indian women.