Annotated Patent Selections

    January 2000 in “ Expert Opinion on Therapeutic Patents ”
    Image of study
    TLDR The document highlights various patents for new compounds with potential treatments for multiple diseases, including cancer, hormonal disorders, and diabetes.
    The document "Annotated Patent Selections" from January 1, 2000, summarized various patents for novel compounds and their potential therapeutic uses. Highlights included treatments for prostate cancer, benign prostatic hyperplasia, breast cancer, precocious puberty, endometriosis, uterine fibroids, acne, premenstrual syndrome, polycystic ovary syndrome, and thrombotic disorders. Specific compounds were claimed to inhibit enzymes like Factor Xa, thrombin, and serine proteases, showing promising IC50 values in vitro. Additionally, patents covered inhibitors of cyclin-dependent kinases for tumor treatment, erythromycin derivatives for hormone-related conditions, and novel inhibitors for Type 3 and 5 17β-hydroxysteroid dehydrogenase targeting androgenic alopecia and other conditions. The document also included claims for compounds targeting diabetes, cancer, inflammatory diseases, and viral infections, with detailed synthesis methods and specific compounds exemplified.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community Quit vaping/smoking = 80% less loss

      in Research/Science  235 upvotes 7 months ago
      Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

      community Bile Acid-Mediated DHT Dysregulation Hypothesis

      in Research/Science  13 upvotes 2 weeks ago
      Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

      community DHT and 5AR respect post, it's importance within the brain

      in Research/Science  111 upvotes 8 months ago
      The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

      community Why is human evolution like this 😂

      in Chat 2 years ago
      Why androgenic alopecia affects the scalp rather than other body parts, potential explanations for this phenomenon, treatments available to combat hair loss, and the implications of male attractiveness in modern society.

    Similar Research

    5 / 1000+ results