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This review presents clinical and preclinical evidence supporting innovative regenerative approaches to treat vitiligo, as existing treatments lack a specific cure and predictable long-term repigmentation outcomes.

This review summarizes recent research on the molecular properties and functions of L-PGDS and PGD2, but reports no new findings, highlighting their pathophysiological roles and guiding future studies.

This study found that during amelogenesis in Msx2 null mice, a dysfunctional enamel organ developed due to abnormal epithelial transformation and lacked proper enamel formation.

In this study, ALR was found to enhance both the proliferation and osteogenic differentiation of mouse bone marrow mesenchymal stem cells, potentially through specific signaling pathways.

This literature review compiles and analyzes current research on turmeric essential oil's active compounds, reporting their potential therapeutic applications across various medical conditions due to their unique pharmacological profiles and absence of toxicity.

This study found that differences in cashmere fiber diameter in Tibetan cashmere goats are associated with variations in metabolic, hypoxic, and stress response-related proteins, offering insights for breeding strategies.

This review highlights the potential of Asteraceae plants as antidiabetic agents and their beneficial effects on conditions such as cardiovascular disease and liver cirrhosis, suggesting their use as food and nutraceuticals could help manage diabetes.

This review discusses how recent advancements in computational and lab-based methods have enhanced peptide drug discovery, noting the efficiency and cost benefits over traditional approaches and the potential for targeting difficult protein interactions, including protein degradation using proteolysis-targeting chimeras.

This study observed that Epigallocatechin-3-gallate (EGCG) can inhibit phosphorylation of STAT1 and reduce a specific subset of immune cells in vitro and ex vivo, suggesting a potential role in maintaining immune privilege in alopecia areata.

This review highlights the need for improved methods in cosmetic safety assessment, emphasizing the potential of engineered skin tissue for more effective detection and toxicological evaluation of cosmetic products, compared to traditional methods.

This review examined the pathological effects of mechanical pressure on human skin at the cellular level, highlighting how various skin cell types respond to pressure, potentially leading to pathological changes such as inflammation, ischemia, and impaired differentiation.

This study identified seven potential enzyme inhibitors from a Polygonum cuspidatum extract using ultrafiltration combined with high-performance liquid chromatography. These compounds showed inhibitory activity against tyrosinase, α-glucosidase, and xanthine oxidase, with most discovered in this extract for the first time.

This mathematical model of alopecia areata illustrates how inflammatory autoimmune responses interrupt the anagen phase of hair growth, and may help evaluate treatments and identify new therapeutic targets.

In this study, researchers examined chicken feather follicle tissues from differently colored chickens and found that the genes SLC45A2 and GPNMB are involved in promoting melanin deposition, which enriches understanding of the genetic mechanisms affecting feather color.

This review discusses the pathogenesis of melasma, including genetic, environmental, and hormonal factors, and highlights potential avenues for new treatments and preventive strategies, but reports no new experimental findings.

This review discusses managing prostate cancer in patients with high-risk germline mutations and highlights the need for more research and consensus guidelines, reporting no new clinical results.

This review discusses the role of extracellular vesicles in bone regeneration and their potential as therapeutics, highlighting challenges like standardization and safety for clinical application, but it reports no new clinical results.

This review explores epidermolysis bullosa simplex subtypes caused by mutations in KRT5 or KRT14 and summarizes gene expression patterns and molecular mechanisms, without presenting new experimental results.

This review summarizes recent findings on how the dysregulated PI3K/Akt/mTOR pathway contributes to immune-mediated inflammatory skin disorders and discusses the potential of natural products, synthetic compounds, and biologic agents in their treatment. However, it emphasizes the need for further research to develop effective therapies.

This study found that Sox2 within dermal papilla cells in the hair follicle regulates hair pigmentation, influencing the type and production of melanin.

In this review, researchers explored how PGC-1α might improve aged skin barrier function by influencing mitochondrial function and reducing inflammation, factors that are linked to epidermal health during aging.

This review reports no new results but highlights the secretory function of keratinocytes, focusing on how various secretions, notably growth factors, impact stem cell differentiation into keratinocytes.

This review discusses the potential of extracellular vesicles for facial aesthetic applications, including scar reduction and skin rejuvenation, but reports no new clinical results; further research into production and mechanisms is needed.

This review discusses how targeting protein degradation processes may help overcome cancer drug resistance, but reports no new clinical results and suggests further research for precise therapeutic strategies.

This review explored the relationship between autoimmune thyroiditis and various autoimmune skin conditions, highlighting shared genetic markers and immunological mechanisms, such as disrupted immune tolerance and oxidative stress, which may contribute to the development of these disorders.

This review evaluates traditional uses, phytochemical profiles, and pharmacological activities of Mediterranean Erica species, revealing the wide range of bioactive compounds and highlighting their antioxidant, anti-inflammatory, and antimicrobial activities. Further studies are suggested to fully understand their medicinal potential.

In this study, voglibose, commonly used for diabetes management, was found to reduce melanin synthesis and inhibit melanogenic signaling pathways in B16F10 melanoma cells, suggesting it could be repurposed for treating hyperpigmentation disorders with confirmed topical safety in human tests.

This study found that extracts from Hom Thong banana peels, rich in phenolic compounds, may inhibit melanin production in human and mouse melanoma cells, showing potential as anti-melanogenic agents comparable to standard treatments like arbutin and kojic acid.

This review discusses the role of cutaneous and intestinal microbiota in the development of alopecia areata, summarizing current literature without reporting new clinical results.

This study found that human induced pluripotent stem cells differentiated precisely to express certain markers during a specific window could enable successful hair follicle generation when transplanted.