Pathological Mechanisms Involved in Epidermolysis Bullosa Simplex: Current Knowledge and Therapeutic Perspectives

    August 2024 in “ International Journal of Molecular Sciences ”
    Mbarka Bchetnia, Julie Powell, Catherine McCuaïg … Catherine Laprise
    Studysummary This review explores epidermolysis bullosa simplex subtypes caused by mutations in <i>KRT5</i> or <i>KRT14</i> and summarizes gene expression patterns and molecular mechanisms, without presenting new experimental results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 3

    1. Keratins as an Inflammation Trigger Point in Epidermolysis Bullosa Simplex International Journal of Molecular Sciences · 2021
    2. Bone Morphogenetic Protein Antagonist Noggin Promotes Skin Tumorigenesis Via Stimulation Of The Wnt And Shh Signaling Pathways American Journal Of Pathology · 2009
    3. Epidermolysis Bullosa Simplex: A Paradigm for Disorders of Tissue Fragility ˜The œJournal of clinical investigation/˜The œjournal of clinical investigation · 2009

    Related research 1

    1. Keratin and Skin Disorders Cell biology international · 1996