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Akt2 protein is essential for normal cell division in early mouse embryos.

Researchers discovered potential origins and new treatments for skin cancer, including biomarkers for melanoma and therapies that reduce tumor growth.

The study found that women with hyperandrogenic PCOS have higher levels of AKT1 and AKT2 proteins in their cells, which may lead to cell dysfunction.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

XIST RNA helps regenerate hair follicles by targeting miR-424 and activating hedgehog signaling.

Understanding hair biology is key to developing better treatments for hair and scalp issues.

The research provides insights into hair follicle growth in forest musk deer by identifying key genes and pathways involved.

The study found that certain microRNAs are higher in the cells and lower in the fluid of women with a specific type of polycystic ovary syndrome, and one microRNA could potentially help diagnose the condition.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

Multi-omics techniques help understand the molecular causes of androgenetic alopecia.

Tadalafil and Finasteride may help treat aggressive melanoma.

Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.

The conclusion is that androgenetic alopecia and senescent alopecia have unique gene changes, suggesting different causes and potential treatments for these hair loss types.

Increased HIF-1α is linked to the inflammation and severity of hidradenitis suppurativa, suggesting treatments that lower HIF-1α could help.

A specific RNA molecule, circCOL1A1, affects the growth and quality of goat hair by interacting with miR-149-5p and influencing cell growth pathways.

FOXO1 is important for wound healing, but its dysfunction in diabetes can slow the healing process.

Researchers developed a cost-effective 66 K SNP chip for cashmere goats that is accurate and useful for genetic studies.

Deleting the PTEN gene in mice causes nerve cells to grow larger and heal better after injury, but may cause overgrowth and hair loss in older mice.

Anthocyanins from fruits and vegetables may help prevent and treat colorectal cancer safely.

Certain gene variations in AKT2 are more common in women with PCOS and are linked to higher levels of specific hormones and symptoms.

MK-2206 was safe and effectively blocked AKT signaling in cancer patients, warranting more trials.

The document concludes that understanding genetic mutations in the PI3K-AKT-mTOR pathway can lead to better diagnosis and treatment for certain genetic skin disorders.

Blocking miR-27a increases sheep hair follicle stem cell growth and decreases cell death, which could help improve wool quality and treat hair loss.

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

Natural volatiles and essential oils have health benefits and can enhance the effects of some medicines, but more research is needed to understand how they work and their possible side effects.

A special gene region controls the re-emergence of a primitive wool type in Merino sheep, improving their wool yield and adaptability.

Platelet-rich plasma therapy is more effective than minoxidil lotion for increasing hair count in men with hair loss, with mild side effects and high satisfaction.

Mast cells and CD8 T cells interact closely in skin diseases, affecting each other's behavior and contributing to conditions like psoriasis and eczema.