129 citations,
July 2019 in “Stem Cell Research & Therapy” Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.
82 citations,
March 2013 in “PLoS ONE” Vemurafenib causes skin side effects similar to RASopathies, requiring regular skin checks and UVA protection.
78 citations,
August 2014 in “Anais Brasileiros de Dermatologia” New vitiligo treatments focus on controlling immune damage and restoring skin color.
61 citations,
October 2011 in “Experimental dermatology” Scalp itching is common and hard to diagnose due to the complex nerve structure of the scalp.
58 citations,
March 2011 in “Pflügers Archiv für die gesamte Physiologie des Menschen und der Tiere/Pflügers Archiv” Hormones and signaling pathways control sebaceous gland function and could help treat acne.
53 citations,
January 2013 in “Journal of toxicologic pathology” The project created a standardized system for classifying skin lesions in lab rats and mice.
45 citations,
November 2021 in “Fertility and Sterility” The conclusion is that women under 35 should start fertility checks after 12 months of trying to conceive, women over 35 after 6 months, and women over 40 should start immediately. The checks should include ovulation status, reproductive tract structure, and male partner's semen evaluation.
44 citations,
October 2019 in “International Journal of Molecular Sciences” Melatonin, usually known for sleep regulation, also has antioxidant properties that can protect skin, stimulate hair growth, and improve skin conditions, with topical application being more effective than oral use.
34 citations,
January 2012 in “Journal of the American Academy of Dermatology” Sarcoidosis is more common and severe in Black patients than in Caucasians, requiring early diagnosis and treatment.
31 citations,
August 2021 in “Stem Cell Research & Therapy” The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
31 citations,
August 2015 in “Stem Cells Translational Medicine” Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.
27 citations,
July 1997 in “PubMed” The harlequin ichthyosis mouse mutation causes thick skin and early death, resembling a human skin disorder.
26 citations,
February 2015 in “Pediatric blood & cancer” Targeted anticancer therapies in children often cause skin side effects like rash and dry skin.
22 citations,
May 2008 in “Acta veterinaria Scandinavica” English springer spaniels are more prone to severe sebaceous adenitis than standard poodles.
21 citations,
November 2017 in “Cochrane library” Ovarian drilling surgery is not clearly better than medical treatments for PCOS symptoms.
16 citations,
October 2023 in “Molecular cancer” New treatments like nanotechnology show promise in improving skin cancer therapy.
15 citations,
September 2014 in “PloS one” The study found that analyzing certain cell signaling pathways is not a reliable method to tell apart two types of skin tumors.
14 citations,
June 2022 in “BMC genomics” Key genes crucial for sheep hair follicle development were identified, aiding fine wool breeding and human hair loss research.
14 citations,
March 2022 in “Clinical Endocrinology” The document concludes that a systematic approach is crucial to identify causes of androgen excess in women beyond the most common cause, Polycystic ovary syndrome (PCOS).
14 citations,
December 2021 in “International journal of molecular sciences” Growth hormone levels affect hair growth and loss, with too much causing excess hair and too little leading to hair loss.
14 citations,
February 2003 in “Journal of the American Academy of Dermatology” Folliculotropic mycosis fungoides can affect the central nervous system in advanced stages.
10 citations,
September 2022 in “Advanced Healthcare Materials” Current methods can't fully recreate skin and its features, and more research is needed for clinical use.
9 citations,
August 2021 in “Journal of clinical medicine” Pili torti is a rare condition where hair is twisted and breaks easily, often linked to genetic disorders or other health issues.
7 citations,
November 2011 in “Archives of Dermatology” Alopecia areata caused a boy's hair to regrow straight instead of curly, but the exact reason is unknown.
6 citations,
January 2019 in “F1000Research” High triglyceride levels are a key factor affecting testosterone levels in women with PCOS.
5 citations,
July 2022 in “Journal of Clinical Medicine” Long COVID-19 patients with skin pain might have a nerve condition that responds to a medication called gabapentin.
5 citations,
July 2022 in “Orphanet journal of rare diseases” RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.
5 citations,
January 2021 in “Frontiers in cell and developmental biology” Skin cysts might help advance stem cell treatments to repair skin.
5 citations,
January 2017 in “Acta Endocrinologica” High androgen levels in postmenopausal women may suggest an ovarian tumor, and removing it can improve heart and metabolic health.
4 citations,
August 2022 in “International Journal of Molecular Sciences” Human foreskin does not show aging or reduced cell growth after radiation, and H2A.J is not a good marker for radiation-induced aging.