New Histopathological Findings in Scarring Alopecias

    January 2024 in “ Archives of pathology & laboratory medicine ”
    Annelise de Almeida Verdolin, Nadia El Kadi, Ronir Raggio Luiz, Chloe Ekelem, Luciana Pantaleão, Maria Fernanda Reis Gavazzoni Dias
    Image of study
    TLDR New findings may help diagnose and understand scarring alopecia better.
    The study investigated histopathological features in 71 female scalp biopsies from 2016 to 2022, focusing on three types of scarring alopecias: frontal fibrosing alopecia (FFA), fibrosing alopecia in a pattern distribution (FAPD), and lichen planopilaris (LPP). The researchers found that adipose tissue infiltration in the dermis at the level of the isthmus and in the bundles of the arrector pili muscle, along with the displacement of eccrine sweat gland coils (ESGCs), were more frequently observed in FFA, followed by FAPD, and less frequently in LPP. These findings suggest that these histopathological changes may play a role in the development of scarring alopecia.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 400 results
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community How essential is scalp biopsy when dealing with hair loss?

      in Treatment  6 upvotes 3 weeks ago
      The user experienced hair loss despite using Fin and Min for 12 years and switched to Dutasteride, RU58841, and Keto scalp serum, but shedding and itch persist. They are considering increasing Dutasteride to 2.5mg and questioning the necessity of a scalp biopsy, with mixed opinions on its usefulness.

      community 9 months on Fin - no progress , should I get on Dutasteride?

      in Chat  10 upvotes 2 weeks ago
      The user has been using finasteride, minoxidil, and nizoral for hair loss but hasn't seen regrowth, only maintenance. They are considering switching to dutasteride, which is believed to be more effective, but are concerned about potential side effects.

      community Fibrosing alopecia in a pattern distribution

      in Research/Science  14 upvotes 7 months ago
      A user has been experiencing hair loss for 4 years, with treatments like minoxidil, finasteride, and various supplements proving ineffective. They were diagnosed with fibrosing alopecia in a pattern distribution, a condition that may require a combination of anti-inflammatory and hair growth treatments.

      community I tried salt water to stop the DHT itch

      in Treatment  60 upvotes 1 year ago
      Treating the itch associated with male pattern baldness, which is believed to be caused by DHT. Potential treatments discussed include salt water, finasteride, ketoconazole, and RU58841.

      community scarring alopecia awareness in this community

      in Chat  33 upvotes 2 years ago
      Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

    Related Research

    3 / 3 results