New Histopathological Findings in Scarring Alopecias
January 2024
in “
Archives of pathology & laboratory medicine
”
Studysummary This study observed that adipose tissue infiltration and ESGC displacement in scalp biopsies were more frequently found in frontal fibrosing alopecia and may play a role in the development of scarring alopecia.
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The study investigated histopathological features in 71 female scalp biopsies from 2016 to 2022, focusing on three types of scarring alopecias: frontal fibrosing alopecia (FFA), fibrosing alopecia in a pattern distribution (FAPD), and lichen planopilaris (LPP). The researchers found that adipose tissue infiltration in the dermis at the level of the isthmus and in the bundles of the arrector pili muscle, along with the displacement of eccrine sweat gland coils (ESGCs), were more frequently observed in FFA, followed by FAPD, and less frequently in LPP. These findings suggest that these histopathological changes may play a role in the development of scarring alopecia.
