New Histopathological Findings in Scarring Alopecias

    January 2024 in “ Archives of pathology & laboratory medicine ”
    Annelise de Almeida Verdolin, Nadia El Kadi, Ronir Raggio Luiz, Chloe Ekelem, Luciana Pantaleão, Maria Fernanda Reis Gavazzoni Dias
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    TLDR New findings may help diagnose and understand scarring alopecia better.
    The study investigated histopathological features in 71 female scalp biopsies from 2016 to 2022, focusing on three types of scarring alopecias: frontal fibrosing alopecia (FFA), fibrosing alopecia in a pattern distribution (FAPD), and lichen planopilaris (LPP). The researchers found that adipose tissue infiltration in the dermis at the level of the isthmus and in the bundles of the arrector pili muscle, along with the displacement of eccrine sweat gland coils (ESGCs), were more frequently observed in FFA, followed by FAPD, and less frequently in LPP. These findings suggest that these histopathological changes may play a role in the development of scarring alopecia.
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