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PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.

Muscles can make their own androgens, which may help muscle growth.

sPLA2-X is crucial for normal hair growth and follicle health.

IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.

Mice without certain skin enzymes have faster hair growth and bigger eye glands.

Growth hormone levels affect hair growth and loss, with too much causing excess hair and too little leading to hair loss.

Inorganic-based biomaterials can quickly stop bleeding and help wounds heal, but they may cause issues like sharp ion release and pH changes.

Retinoic acid affects male and female muscle energy use and function differently.

Personalized diets, like the Mediterranean Diet and low carb diets, can help manage PCOS symptoms in obese women, and probiotics may enhance weight loss and improve metabolic health. More research is needed to find the best diet strategies.

Non-surgical procedures can help reduce wrinkles and stimulate skin repair by understanding skin aging at the molecular level.

Natural products may help treat skin inflammation from abnormal adrenal hormones.

Hydrogels combined with extracellular vesicles and 3D bioprinting improve wound healing.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

PRP and PRF show promise for hair growth but need more research for consistent and safe use.

Hormones like androgens, estrogen, thyroid hormones, and stress hormones can contribute to hair loss, and treatments target these hormonal imbalances.

Proper nutrition can help manage PCOS symptoms and improve overall health.

The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.

Cactus extract from Notocactus ottonis may help promote hair growth.

Central lipohypertrophy in HIV-infected women may lead to shorter eyelashes.

Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.

Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.

Different treatments for Hidradenitis suppurativa range from antibiotics and hormonal therapies to surgery, depending on severity.

Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.

The project created a standardized system for classifying skin lesions in lab rats and mice.

Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.

Disrupting the Flcn gene in mice causes early kidney cysts and tumors, which can be treated with rapamycin.

Perilla frutescens, an East Asian plant, contains 400 bioactive compounds that have various health benefits, including anti-inflammatory, antidepressant, and anticancer effects, and can treat conditions like diabetes, skin allergies, and neurological disorders.

The document concludes that a systematic approach is crucial to identify causes of androgen excess in women beyond the most common cause, Polycystic ovary syndrome (PCOS).

PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.