56 citations
,
January 2021 in “Clinical and Experimental Medicine” This review highlights the challenges in treating alopecia areata, noting that current therapies often lead to relapse and have uncertain long-term effectiveness; it also points to potential future treatments such as JAK-STAT inhibitors and PRP.
8 citations
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August 2019 in “Dermatologic surgery” This review covers nonsteroid-based therapies for alopecia areata, finding potential in PRP, UVR, and laser treatments, but highlights a lack of high-quality evidence for their efficacy.
205 citations
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April 2013 in “British Journal of Dermatology” In this study, platelet-rich plasma significantly increased hair regrowth and reduced symptoms of alopecia areata compared to triamcinolone acetonide or placebo, with no observed side effects.
99 citations
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July 2017 in “Clinical Reviews in Allergy & Immunology” This review noted that alopecia areata is an autoimmune disease impacting hair follicles and offered insights into its complex pathogenesis involving immune responses, while highlighting ongoing research into new treatments such as Janus kinase inhibitors and other immunomodulatory drugs.
15 citations
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July 2022 in “Biomedicines” This study found no significant difference in the severity of alopecia areata between treatments with platelet-rich plasma and triamcinolone acetonide; further high-quality trials of PRP are needed.
1 citations
,
October 2020 in “Journal of Investigative Dermatology Symposium Proceedings” This report from the seventh AA Research Summit discusses research highlights and sets future priorities for managing alopecia areata.
1 citations
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October 2020 in “Journal of Investigative Dermatology Symposium Proceedings” This study found that platelet-rich plasma treatment increased hair density and reduced inflammation in patients with patchy alopecia areata, but not in a patient with alopecia universalis.
September 2025 in “Journal of Skin and Stem Cell” This study found that combining topical calcipotriol with intralesional autologous PRP injection significantly reduced Severity of Alopecia Tool scores in patients with alopecia areata, more effectively than either treatment alone.
February 2023 in “Archives of Dermatological Research” This study found fractional carbon dioxide laser therapy effective in treating alopecia areata, both alone and with topical treatments, suggesting decorin's involvement in improving hair growth.
August 2020 in “International Journal of Dermatology and Venereology” This study found that platelet-rich plasma injections improved alopecia severity scores in women with androgenetic alopecia after six months, though further research is needed to confirm these results.
35 citations
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May 2012 in “Expert Opinion on Pharmacotherapy” This review summarizes current and emerging treatments for common hair loss conditions, highlighting good evidence for androgenetic alopecia but noting the lack of long-term data for alopecia areata and cicatricial alopecias.
27 citations
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January 2020 in “Experimental Dermatology” This review discusses the role of immune cells in mammalian hair cycle control and highlights their potential relevance to human hair cycling disorders, reporting no new clinical findings.
26 citations
,
June 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This review explores regenerative medicine approaches for vitiligo and alopecia areata, focusing on pathways for repopulating melanocytes and regrowing hair follicles, and summarizes potential treatments without reporting new clinical results.
19 citations
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May 2019 in “Journal of Cosmetic Dermatology” In this study, both platelet-rich plasma and intralesional corticosteroids improved hair re-growth in alopecia areata patients, but the difference between treatments was not significant, with fewer relapses observed in the platelet-rich plasma group.
17 citations
,
August 2015 in “Expert Opinion on Pharmacotherapy” This article discusses the social and psychological impact of hair disorders and the challenges in their treatment, but reports no new clinical results.
12 citations
,
June 2018 in “Journal of Cosmetic Dermatology” This review outlines recent research on platelet-rich plasma, alone or combined with other therapies, for managing hair loss disorders, and discusses future prospects without reporting new clinical findings.
5 citations
,
October 2025 in “Expert Review of Clinical Immunology” This article reviews current and emerging treatments for alopecia areata, emphasizing the need for biomarker-driven patient stratification to optimize therapeutic strategies and reduce potential side effects; it reports no new clinical findings.
5 citations
,
July 2025 in “Scientific Reports” This study observed that areas with low socio-demographic index showed the greatest rise in the disease burden of alopecia areata from 1990 to 2019, while high SDI areas still carried the highest burden overall.
5 citations
,
August 2021 in “Clinics in dermatology” This review examines the use of platelet-rich plasma in aesthetic medicine and reports no new clinical results, highlighting the need for further research into its efficacy and safety.
2 citations
,
June 2022 in “Journal of cosmetic dermatology” This case report highlights the onset of alopecia areata following dupilumab treatment, noting the significant temporal link between the medication use and hair loss occurrence.
2 citations
,
June 2019 in “Serbian Journal of Dermatology and Venereology/Serbian Journal of Dermatology and Venerology” This study reported remarkable improvement in three patients with treatment-resistant alopecia areata after receiving autologous platelet-rich plasma injections, suggesting the potential for this approach and a need for further randomized, placebo-controlled trials.
1 citations
,
April 2019 in “Advances in Cosmetic Surgery” Platelet-rich plasma shows potential for hair growth, but more research is needed to determine the best preparation method.
1 citations
,
May 2017 in “InTech eBooks” This review discusses various treatments for noncicatricial alopecias, such as androgenetic alopecia and alopecia areata, including mesotherapy, microneedling, and platelet-rich plasma therapy, noting that outcomes vary across these procedures.
1 citations
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November 2016 in “Saengmyeong gwahag hoeji/Saengmyeong gwahak hoeji” This review discusses new insights into the pathogenesis of alopecia areata related to perifollicular immune and endocrine factors and potential new treatments, but it reports no clinical results.
August 2026 in “Recent Advances in Inflammation & Allergy Drug Discovery” This review discusses various factors influencing alopecia areata and explores newer therapeutic options like biologics and regenerative techniques, but it reports no new clinical trial results.
July 2026 in “Quality in Sport” This review reports that Janus kinase inhibitors and regenerative therapies, such as exosomes and platelet-rich plasma, significantly improve scalp hair regrowth in moderate-to-severe alopecia areata, though challenges like high relapse rates and socioeconomic barriers remain, underscoring the need for personalized treatment protocols.
January 2026 in “Journal of Aesthetic Nursing” This case report observed marked hair regrowth in a patient with refractory alopecia areata using a combination of platelet-rich plasma, low-level light therapy, and microneedling alongside topical and oral agents.
January 2026 in “Digital Repository (National Repository of Grey Literature)” In this study, two formulations of platelet-rich plasma and two mesotherapy products showed varying degrees of effectiveness in improving hair thickness, density, and count in androgenetic alopecia patients after six months, with MZT1 and PRP2 achieving statistically significant improvements in most measures.
December 2025 in “Cosmetics” This review synthesizes recent molecular and preclinical advances in alopecia areata and androgenetic alopecia, highlighting how interventions targeting specific intracellular signaling pathways and utilizing stem cell technologies can support precision regrowth and structural follicle reconstruction.
November 2025 in “Journal of Investigative Dermatology” This case series observed that five Black pediatric patients with moderate to severe alopecia areata showed significant hair regrowth and minimal disease activity after treatment with topical JAK inhibitors, vitamin D supplementation, and antihistamines, with additional therapies in some cases.