Modified Platelet Rich Plasma Therapy for Alopecia Totalis

    Avita Dhiman, Manmohan Bagri
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    TLDR The combined treatment helps improve severe hair loss and reduces the need for other medications.
    The study presents a case of a female in her late twenties with alopecia totalis treated with a combination of modified platelet-rich plasma (PRP) and intralesional triamcinolone acetonide (TrA). Initial treatments with prednisolone, azathioprine, and minoxidil showed temporary improvement, but hair loss recurred upon tapering steroids. Modified PRP, prepared by a double spin method and combined with TrA, was administered intradermally. After four sessions at four-week intervals, significant hair regrowth and increased density were observed, allowing for the tapering of systemic steroids. The study concludes that modified PRP with TrA is a promising treatment for alopecia totalis, promoting early regrowth and reducing the need for prolonged immunosuppressant use. However, larger studies with longer follow-ups are needed to confirm these benefits.
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      community Do Platelet-rich plasma, PRP work?

      in Research/Science  14 upvotes 1 year ago
      Someone's brother tried Platelet-rich plasma (PRP) for hair loss; it had minimal effect on hair but improved skin appearance. Microneedling at home was suggested as a more sustainable alternative.

      community Thoughts on platelet-rich plasma therapy

      in Treatment  3 upvotes 3 weeks ago
      Platelet-rich plasma (PRP) therapy for hair loss is expensive, painful, and often ineffective, with mixed reviews on its benefits. Alternatives like minoxidil, finasteride, and hair transplants are suggested as more reliable options.

      community Why can't you drink caffeine after PRP?

      in Treatment  9 upvotes 2 years ago
      The conversation discusses avoiding caffeine after Platelet-Rich Plasma (PRP) treatment for hair loss because caffeine is a vasoconstrictor, which can reduce blood flow and hinder the healing process that PRP aims to promote.

      community I just made my own PRP - DIY PRP

      in Research/Science  549 upvotes 1 year ago
      The post and conversation are about a user who made their own Platelet-Rich Plasma (PRP) for hair loss treatment at home, using their own blood and a centrifuge. The responses vary, with some users supporting the DIY approach to save money, others expressing concern about the safety and effectiveness of the method, and a few joking about the lengths people will go to combat hair loss.

      community Anyone have PRP/Exosome results to share?

      in Treatment  3 upvotes 1 year ago
      Considering alternative treatments to hair loss, such as platelet-rich plasma (PRP) and exosome therapy, instead of using medications like minoxidil, finasteride/dutasteride.

      community Most Recent Interesting Hairloss Studies: 10% Minox vs 5% Minox / Radio Rrequency Treatment for AA / Topical Ketoconazole / PRP+Minox vs Minox vs PRP / Alopecia as a systemic disease

      in Treatment  90 upvotes 4 years ago
      Treatments for hair loss, such as topical minoxidil, platelet-rich plasma therapy with or without minoxidil, ketoconazole, non-abative radio frequency, natural products, finasteride and cortexolone 17 alpha propionate. The post evaluates the efficacy and safety of these treatments in various studies.

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