Modified Platelet Rich Plasma Therapy for Alopecia Totalis

    Avita Dhiman, Manmohan Bagri
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    TLDR The combined treatment helps improve severe hair loss and reduces the need for other medications.
    The study presents a case of a female in her late twenties with alopecia totalis treated with a combination of modified platelet-rich plasma (PRP) and intralesional triamcinolone acetonide (TrA). Initial treatments with prednisolone, azathioprine, and minoxidil showed temporary improvement, but hair loss recurred upon tapering steroids. Modified PRP, prepared by a double spin method and combined with TrA, was administered intradermally. After four sessions at four-week intervals, significant hair regrowth and increased density were observed, allowing for the tapering of systemic steroids. The study concludes that modified PRP with TrA is a promising treatment for alopecia totalis, promoting early regrowth and reducing the need for prolonged immunosuppressant use. However, larger studies with longer follow-ups are needed to confirm these benefits.
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      community Thoughts on platelet-rich plasma therapy

      in Treatment  3 upvotes 1 year ago
      Platelet-rich plasma (PRP) therapy for hair loss is expensive, painful, and often ineffective, with mixed reviews on its benefits. Alternatives like minoxidil, finasteride, and hair transplants are suggested as more reliable options.

      community Anyone have PRP/Exosome results to share?

      in Treatment  3 upvotes 3 years ago
      Considering alternative treatments to hair loss, such as platelet-rich plasma (PRP) and exosome therapy, instead of using medications like minoxidil, finasteride/dutasteride.

      community Went from almost balding to some this!

      in Progress Pictures  498 upvotes 2 years ago
      A user successfully regrew hair after nearly going bald by using oral finasteride, topical minoxidil, plasma injections, and mesotherapy over 9 months. They plan to try derma rolling and have an alarm set for taking medication, noting increased sexual drive as a side effect.

      community Shedding ALOT of hairs after 2nd session of PRap

      in Is this regrowth? 2 years ago
      After a second session of Platelet-Rich Plasma (PRP) treatment for hair regrowth, the user is experiencing increased shedding of thick and dark hairs and is concerned about whether this is temporary. They are seeking others' experiences with PRP, specifically regarding the duration of shedding and eventual positive outcomes.

      community Finasteride user thinking of going on Minoxidil: custom version vs. generic?

      in Minoxidil  9 upvotes 2 years ago
      A man in his 50s, who has been on Finasteride for 15 years, is considering adding a custom topical Minoxidil blend to his treatment due to recent hairline recession. He questions whether the custom blend is more effective than generic Minoxidil, expresses concerns about shedding and body hair growth, and seeks advice on application timing with styling products and whether to pursue other treatments like PRP or laser.

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