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The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.

Finasteride boosts morphine's pain relief, stops tolerance, and reduces withdrawal in rats.

Finasteride doesn't affect erections much, but may decrease libido in men.

The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.

5α-reductase inhibitors like finasteride may not be effective or safe for transgender individuals, and more research is needed.

New compounds were made that effectively block a specific enzyme related to androgen conditions.

5α-reductase inhibitors can interfere with doping tests by masking banned substances.

Reducing 5α-reductase activity helps endometrial cells differentiate, aiding pregnancy.

The PW91 method is best for calculating the basic physical and chemical properties of Finasteride, a drug used for prostate issues and hair loss.

HST and HST/F promote hair growth and may help treat alopecia.

Finasteride's sexual side effects not caused by androgen deficiency or SRD5A inhibition.

5α-reductase inhibitors may prevent prostate cancer but could also raise the risk of more severe cancers.

Finasteride safely lowers DHT levels without affecting testosterone.

Finasteride effectively blocks enzyme causing male pattern baldness.

Male pattern baldness involves hormones and cell signals affecting hair growth.

Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.

Four-amino acid part makes enzyme sensitive to finasteride.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

Finasteride reduces hairiness and androgen levels in women with unexplained excessive hair growth.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.

Antidepressants, 5α-reductase inhibitors, and isotretinoin can cause long-lasting sexual dysfunction.

Ginseng, especially red ginseng, may help regrow hair and block a hair loss-related enzyme.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.