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The document concludes that specific methods for making diazine-based drugs can lead to high yields and are important for creating effective treatments for various diseases.

Methylated flavonoids may effectively reduce depression and inflammation caused by finasteride.

Juglone from walnut extracts may help repair damaged hair.

Heavy ion radiation has a more severe and long-lasting effect on mouse intestinal metabolites than gamma radiation.

Four natural compounds were found to promote hair growth effectively.

Adding cerium(III) chloride to Grignard reagents improves the making of compounds that could treat prostate issues and hair loss.

Finasteride potentially treats hair loss by reducing DHT production.

Compounds from the plant Mammea siamensis may help treat hair loss.

The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.

Compound 15a was effective in inhibiting 5α-reductase.

Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.

The study created a new method to test drugs that affect hormone processing in skin.

Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Certain drugs that block specific enzymes can help treat prostate diseases.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.

Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.

Low dose finasteride decreases certain steroids, possibly increasing depression risk.

The compound 4c showed strong potential as an anticancer agent.

Glioblastoma cells can make androgens, which might help the tumor grow.

A new method accurately measures nine specific hormones in human blood.

The side gland of Suncus murinus is a good model for studying human sebaceous glands.

Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

A new method was developed to make finasteride for treating hair loss.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

Scientists found out the structure of a human enzyme linked to prostate cancer and hair loss, which could help in designing drugs.