research Differential Distribution of the Epigenetic Marker 5-Hydroxymethylcytosine in Hair Follicle Stem Cells During Bulge Activation
The marker 5-hmC changes in hair follicle stem cells when they start to grow.
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research Hair Are the Rankings—5-Alpha Reductase Inhibitors and Minoxidil in Male Androgenetic Alopecia
Minoxidil and finasteride are FDA-approved treatments for male hair loss, but off-label use of oral minoxidil, dutasteride, and higher doses of finasteride and minoxidil is increasing.
research In Silico Screening of Effective Inhibitor of 5α-Reductase Type 1 for Androgenic Alopecia Treatment
β-sitosterol and brassicasterol may help treat hair loss.
research Dual Wavelength LEDs Induce Reactive Oxygen Species and Nitric Oxide That Inhibit the Production of Dihydrotestosterone by 5-Alpha Reductase
Dual wavelength LEDs may help reduce hair loss by lowering DHT levels.
research A Comparative Study on the Efficacy and Safety of 10% Topical Minoxidil Versus 5% Topical Minoxidil in the Treatment of Male Pattern Hair Loss
10% minoxidil improves frontal hair count more than 5% but has more side effects.
research Emerging and Traditional 5-Alpha Reductase Inhibitors and Androgen Receptor Antagonists for Male Androgenetic Alopecia
New treatments for male hair loss are being explored to improve effectiveness and reduce side effects.
research Sexual Dysfunction With 5-Alpha-Reductase Inhibitor Therapy for Androgenetic Alopecia: A Global Propensity Score Matched Retrospective Cohort Study
Taking medication for hair loss might cause sexual problems.
research Phytotherapeutic Alternatives to the Use of Finasteride and Dutasteride as 5-Alpha Reductase Inhibitors in the Treatment of Androgenetic Alopecia: A Review
Some plant-based products might treat hair loss with fewer side effects than current medications.
research Adverse Effects of the 5-Alpha-Reductase Inhibitor Finasteride on Daphnia Magna: Endocrine System and Lipid Metabolism Disruption
Finasteride harms Daphnia magna's reproduction and metabolism.
research Fructus Psoraleae Treating Androgenetic Alopecia Through 5-Alpha Reductase Inhibition and Nrf2-Keap1 Pathway
Fructus Psoraleae may help treat hair loss by inhibiting 5-α reductase and affecting the Nrf2-Keap1 pathway.
research Evaluation of the Efficacy of Microneedling Without and With Minoxidil 5% and Autologous Platelet-Rich Plasma for Androgenetic Alopecia in Men
Platelet-rich plasma treatment significantly thickens hair shafts.
research A Randomized Control Trial Comparing the Efficacy of Platelet-Rich Plasma and 5% Topical Minoxidil for the Treatment of Androgenetic Alopecia
Platelet-rich plasma therapy works better than minoxidil for hair loss treatment in the tested group.
research Antialopecia Activity Exploration by In-Silico Analysis of Bioactive Compounds from Sansevieria Trifasciata Prain Leaves Through 5α-Reductase Inhibition
Methyl pyropheophorbide A from Sansevieria trifasciata leaves may help treat hair loss.
research Inhibitor of 5α-Reductase Dutasteride in the Treatment of Benign Prostatic Hyperplasia: Systematic Review and Meta-Analysis
Dutasteride is more effective than finasteride for treating BPH without extra safety risks.
research 5 Alpha-Reductase Inhibitors
5 Alpha-Reductase Inhibitors reduce the effects of testosterone by blocking its conversion into a stronger form.
research Alpha Blocker and 5-Alpha Reductase Inhibitor Prescribing Habits Among Urologists and Primary Care Physicians
Urologists prescribe newer medications more often than primary care physicians, who could benefit from more education on treatment options.
research 5 Best Hair Growth Products in 2021: Read Before You Make a Choice
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research Histomorphometrical Evaluation of the Corpus Cavernosum of Hypertensive Rats Treated with 5-Alpha-Reductase Inhibitors
5-alpha-reductase inhibitors significantly affect the penile tissue of hypertensive rats.
research Histomorphometrical Evaluation of the Corpus Cavernosum of Hypertensive Rats Treated with 5-Alpha-Reductase Inhibitors
SHH protein helps nerve regeneration in hypertensive rats.
research Screening of Steroid 5-Reductase Inhibitory Activity and Total Phenolic Content of Thai Plants
Ocimum basilicum L. and red Oryza sativa L. may help with hair loss and prostate issues.
research Topical MK-386, an Inhibitor of 5α-Reductase Type I, Suppresses Sebum DHT
MK-386 reduces sebum DHT levels.
research A Review on Finasteride: A 5-Alpha Reductase Inhibitor, Its Mechanism, Facts, and Benefits
Finasteride effectively treats hair loss and prostate issues with minimal side effects.
research Change in Hair Growth-Related Gene Expression Profile in Human Isolated Hair Follicles Induced by 5-Alpha Reductase Inhibitors, Dutasteride and Finasteride, in the Presence of Testosterone
Dutasteride and finasteride can change hair growth genes, helping treat hair loss.
research Extramammary Paget Disease: Failure to Respond to Topical Imiquimod 5%
Imiquimod 5% cream may not work for treating scrotal extramammary Paget disease.
research A Pilot Study of the Efficacy in Treatment of Female Pattern Hair Loss Using 5% Minoxidil Solution Combined with Oral Chelated Zinc Supplement
Using 5% Minoxidil solution with oral chelated zinc supplement can effectively treat female pattern hair loss.
research A Comparative Study of Efficacy of 5% Minoxidil and 5% Minoxidil Plus Platelet-Rich Plasma in the Same Patient for Treatment of Androgenetic Alopecia
Combining 5% minoxidil with platelet-rich plasma is more effective for hair loss than minoxidil alone.
research A Narrowed Look Into Plant-Derived Testosterone 5α-Reductase Inhibitors for Androgenetic Alopecia
Plant-based treatments might help with hair loss and have fewer side effects than synthetic drugs.
research Clinical Efficacy, Cosmetic Acceptability, and Local Tolerability of a New Formulation of Topical 5% Minoxidil Without Propylene Glycol: A 6-Month, Multicentre, Real-Life, Prospective, Assessor-Blinded Study in 196 Subjects with Hair Loss. The NOMINAL Trial
The new 5% minoxidil formulation without propylene glycol effectively promotes hair growth with fewer side effects and better user satisfaction.
research Attenuation of 5α-Reductase-Mediated Progesterone Metabolism Promotes Differentiation of Human Endometrial Stromal Cells for the Establishment of Pregnancy
Reducing 5α-reductase activity helps endometrial cells differentiate, aiding pregnancy.