Topical MK-386, an Inhibitor of 5α-Reductase Type I, Suppresses Sebum DHT

    Jules I. Schwartz, Barry J. Gertz, Wesley Tanaka, D. Wang, Gregory A. Winchell, Sherilyn Adcock, David L. Ebel, Mary Flynn, M.L. Constanzer
    TLDR MK-386 reduces sebum DHT levels.
    The study investigated the effects of topical MK-386, an inhibitor of 5α-reductase type I, on sebum dihydrotestosterone (DHT) levels. The research was conducted by a team from Merck Research Laboratories and Pharmaco LSR. The findings indicated that MK-386 effectively suppressed sebum DHT, suggesting its potential utility in conditions related to DHT, such as acne and androgenetic alopecia. However, the document did not specify the number of participants involved in the study, which is crucial for assessing the strength of the findings.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 25 results

    Similar Research

    5 / 1000+ results