219 citations
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March 2004 in “Journal of The American Academy of Dermatology” In this 48-week trial, 5% topical minoxidil was more effective than both 2% minoxidil and placebo in promoting hair growth in women with female pattern hair loss, with notable improvements in nonvellus hair count and hair growth assessments.
142 citations
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August 2007 in “Journal of The American Academy of Dermatology” This study found that a new 5% minoxidil foam formulation significantly increased hair counts and improved hair loss condition in men with androgenetic alopecia over 16 weeks compared to placebo.
100 citations
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June 2011 in “Journal of The American Academy of Dermatology” This study found that a once-daily 5% minoxidil topical foam is as effective as a twice-daily 2% minoxidil topical solution for hair growth in women with androgenetic alopecia, with fewer side effects and greater styling convenience.
41 citations
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November 1993 in “Journal of The American Academy of Dermatology” This study found that DPCP treatment led to cosmetically acceptable hair regrowth in 38% of patients with chronic severe alopecia areata, while adding 5% minoxidil showed no significant clinical benefit.
34 citations
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February 1992 in “The Journal of Clinical Endocrinology and Metabolism” In this study, the combination of finasteride and minoxidil significantly increased hair growth in balding male stumptail macaques compared to each drug alone.
28 citations
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October 2017 in “Journal of Cosmetic and Laser Therapy” This study found that combining microneedle treatments with 5% minoxidil topical solution led to the greatest increase in hair density among Chinese men with androgenetic alopecia.
19 citations
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May 2017 in “Dermatologic Surgery” Combining platelet-rich plasma with 5% minoxidil solution improves hair regrowth in androgenetic alopecia patients.
11 citations
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January 2019 in “International Journal of Trichology” This study observed no significant improvement of mesotherapy over 5% topical minoxidil for male androgenic alopecia, despite a small increase in hair shaft diameter variation with mesotherapy.
10 citations
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May 2020 in “Journal of Dermatological Treatment” This study found that combining microneedling with 5% minoxidil improved hair growth in Chinese men with androgenetic alopecia, possibly through activating the Wnt/β-catenin signaling pathway.
8 citations
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October 2015 in “PubMed” Recent Phase III trials reported that once daily 5% minoxidil foam significantly increased hair count in women with female pattern hair loss and was shown to be as effective as twice daily 2% minoxidil solution.
5 citations
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October 2020 in “Lasers in Medical Science” This study found that combination therapy with LLLT and 5% minoxidil improved hair diameter and density more effectively than each treatment alone in women with female pattern hair loss.
4 citations
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July 2022 in “Clinical and Experimental Dermatology” This review examines the efficacy and safety of using minoxidil at concentrations greater than 5% for androgenetic alopecia but reports no new clinical results, emphasizing a need for further research.
4 citations
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January 2016 in “Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.)” This study evaluated the efficacy and safety of a 5% minoxidil topical foam without propylene glycol in men with androgenic alopecia.
3 citations
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April 2021 in “Journal of Cosmetic Dermatology” Combination therapy with QR 678 Neo and 5% Minoxidil is most effective for male hair loss.
3 citations
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February 2021 in “Medical journal, Armed Forces India” In this observational study, the combination of PRP and 5% minoxidil was more effective than minoxidil alone in promoting hair growth in men with androgenetic alopecia.
3 citations
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April 2016 in “PubMed” This study found that a twice-daily regimen of 5% minoxidil foam combined with a botanical hair solution significantly improved hair growth and appearance in men with mild to moderate androgenic alopecia over 12 weeks.
2 citations
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October 2020 in “Dermatologic Therapy” This study found that a topical herbal solution significantly increased hair diameter and density in men with androgenetic alopecia compared to minoxidil after 36 weeks of treatment.
1 citations
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March 2017 in “Journal of evolution of medical and dental sciences” This study compared microneedling combined with platelet-rich plasma and microneedling with minoxidil for treating androgenetic alopecia in men, finding both approaches effectively improved hair density and alopecia grade.
1 citations
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January 2023 in “Indian Journal of Dermatology/Indian journal of dermatology” This case study reported that 5% minoxidil solution effectively promoted hair growth and resulted in generalized hypertrichosis in a 7-year-old with Trichorhinophalangeal syndrome type I.
1 citations
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January 2019 in “Journal of the Egyptian Women's Dermatologic Society (Print)” This study observed that while both minoxidil and botanically-derived 5-alpha reductase inhibitors significantly increased hair count and diameter in women with female pattern hair loss, minoxidil was more effective, especially for greater hair diameter increases, but had more troublesome side effects.
January 2026 in “Dermatologic Therapy” This study reported that combining microneedling with 5% minoxidil solution was safe and effective for treating female pattern hair loss, with 90% of the 40 patients showing hair growth improvements over 12 weeks and no serious adverse reactions.
December 2025 in “Lasers in Medical Science” This study found that combining photobiomodulation therapy with minoxidil significantly improved hair quality and reduced telogen-phase hair counts more effectively than minoxidil alone in women with female pattern hair loss over a shorter 12.5-week period.
February 2025 in “Archives of Dermatological Research” This study found that combining microneedling with 5% Minoxidil and Finasteride significantly improved hair density and hair shaft diameter in males with androgenetic alopecia, outperforming Minoxidil alone or in combination with Finasteride, although changes in hormonal levels and trace elements were not significant.
January 2024 in “Journal of Cosmetic Dermatology” This study reported that the 1565 nm non-ablative fractional laser treatment significantly improved various hair growth indices in patients with androgenetic alopecia compared to 5% minoxidil, demonstrating its superior clinical efficacy and safety for treating this condition.
January 2024 in “Advances in Dermatology and Allergology” This abstract highlights the prevalence of androgenetic alopecia in men and young adults and mentions the psychological impact, noting that while various therapies exist, clear treatment algorithms are lacking according to this source.
January 2026 in “Dermatology Online Journal” Female-marketed minoxidil foam is more expensive than male-marketed, but generic and bulk options can reduce this gap.
June 2025 in “Journal of Cosmetic Dermatology” This study found that among various treatments for male androgenetic alopecia, dutasteride 0.5 mg/day was the most effective option overall. Additionally, among FDA-approved treatments, topical minoxidil 5% was the most effective topical therapy, and finasteride 1 mg/day was the most effective oral therapy.
September 2024 in “Journal of Clinical and Nursing Research” This study found that combining Chuzhi Shengfa Tablets with either ketoconazole shampoo or 5% minoxidil foam significantly improved hair density, hair diameter, and reduced scalp oil in men with androgenetic alopecia, without increasing adverse reactions.
June 2023 in “Journal of Cosmetic Dermatology” This research highlights that while minoxidil and 5-alpha reductase inhibitors are commonly used for treating pattern hair loss, there is limited evidence supporting their relative effectiveness in women compared to men.
May 2023 in “International Journal of Trichology” In this study, 70% of female androgenetic alopecia patients who did not respond to standard minoxidil experienced clinical improvement after switching to a propylene glycol-free, witch hazel-based 5% minoxidil sulfate solution, with the treatment also being well-tolerated.