Microneedling Combined With 5% Minoxidil for Female Pattern Hair Loss: A Retrospective Study on Efficacy and Safety

    January 2026 in “ Dermatologic Therapy ”
    Lulu Yang, Wei Cui, Zhongfa Lu
    Studysummary This study reported that combining microneedling with 5% minoxidil solution was safe and effective for treating female pattern hair loss, with 90% of the 40 patients showing hair growth improvements over 12 weeks and no serious adverse reactions.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on doi.org →
    Discuss this study in the Community →

    Research cited in this study 21

    1. Assessing the Efficacy of Automated Microneedling Monotherapy for Androgenetic Alopecia: A Comparison of 3 Different Depths Dermatologic surgery · 2024
    2. The Boosting Effect of Minoxidil 0.1% Combined With Dutasteride 0.01% and Microneedling in the Treatment of Female Pattern Hair Loss Journal of the Egyptian Women's Dermatologic Society (Print) · 2024
    3. The Relative Effect of Monotherapy with 5-Alpha Reductase Inhibitors and Minoxidil for Female Pattern Hair Loss: A Network Meta-Analysis Study Journal of Cosmetic Dermatology · 2023
    4. Randomized Trial of Microneedling Combined With 2% Minoxidil Topical Solution for the Treatment of Female Pattern Hair Loss in a Chinese Population Journal of Cosmetic Dermatology · 2022
    5. Efficacy and Safety of 5% Minoxidil Alone, Minoxidil Plus Oral Spironolactone, and Minoxidil Plus Microneedling on Female Pattern Hair Loss: A Prospective, Single-Center, Parallel-Group, Evaluator-Blinded, Randomized Trial Frontiers in Medicine · 2022
    6. Microneedling and Its Use in Hair Loss Disorders: A Systematic Review Dermatology and therapy · 2021
    7. The Comparison of Demographics and Comorbidities of Female Pattern Hair Loss According to the Clinical Subtype and Stage Journal of The American Academy of Dermatology · 2021
    8. Prevalence of Female Pattern Hair Loss in a Multiracial Population Journal of The American Academy of Dermatology · 2021
    9. Combination Therapy with Topical Minoxidil and Nano-Microneedle-Assisted Fibroblast Growth Factor for Male Androgenetic Alopecia: A Randomized Controlled Trial in Chinese Patients Chinese Medical Journal · 2020
    10. Microneedling in Androgenetic Alopecia: Comparing Two Different Depths of Microneedles Journal of Cosmetic Dermatology · 2020
    11. Randomized Trial of Electrodynamic Microneedling Combined with 5% Minoxidil Topical Solution for Treating Androgenetic Alopecia in Chinese Males and Molecular Mechanistic Study of the Involvement of the Wnt/β-Catenin Signaling Pathway Journal of Dermatological Treatment · 2020
    12. Microneedling Improves Minoxidil Response in Androgenetic Alopecia Patients by Upregulating Follicular Sulfotransferase Enzymes PubMed · 2020
    13. Minoxidil 1 mg Oral Versus Minoxidil 5% Topical Solution for the Treatment of Female-Pattern Hair Loss: A Randomized Clinical Trial Journal of The American Academy of Dermatology · 2019
    14. Frequency of the Types of Alopecia at Twenty-Two Specialist Hair Clinics: A Multicenter Study Skin appendage disorders · 2019
    15. Female Pattern Hair Loss: A Clinical, Pathophysiologic, and Therapeutic Review International Journal of Women's Dermatology · 2018
    16. Microneedling for the Treatment of Hair Loss Journal of The European Academy of Dermatology and Venereology · 2017
    17. Alopecia Areata and Health-Related Quality of Life: A Systematic Review and Meta-Analysis British Journal of Dermatology · 2016
    18. A Randomized Evaluator Blinded Study of Effect of Microneedling in Androgenetic Alopecia: A Pilot Study International Journal of Trichology · 2013
    19. Effects of Topical Application of Growth Factors Followed by Microneedle Therapy in Women with Female Pattern Hair Loss: A Pilot Study Journal of Dermatology · 2012
    20. Minoxidil Use in Dermatology, Side Effects, and Recent Patents Recent Patents on Inflammation & Allergy Drug Discovery · 2012
    21. A Randomized, Placebo-Controlled Trial of 5% and 2% Topical Minoxidil Solutions in the Treatment of Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2004