Clinical Efficacy of Microneedle Combined with 5% Minoxidil Solution and Finasteride in the Treatment of Androgenetic Alopecia in Males

    February 2025 in “ Archives of Dermatological Research
    Yan Chang, Wenxia Zhang, Jianping Zhou, Linna Lv, Qi He, Y.-C. Chen, Ping Wang, Qing Zhai
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    TLDR Combining microneedling with Minoxidil and Finasteride greatly improves hair growth and reduces hair loss in men.
    The study evaluated the effectiveness of combining microneedling with 5% Minoxidil and Finasteride for treating male androgenetic alopecia, involving 45 male patients divided into three groups. Group A received only 5% Minoxidil, Group B received 5% Minoxidil and Finasteride, and Group C received the combination therapy including microneedling. Results indicated significant increases in hair density and shaft diameter across all groups, with the most improvement in Group C. The Norwood-Hamilton alopecia scale scores were significantly better in Group C compared to Group A, and 80% of patients in Group C reported a score of ≥3, indicating superior outcomes. The study concluded that microneedling combined with Minoxidil and Finasteride significantly enhances hair growth and reduces hair loss, demonstrating substantial clinical value.
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