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Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.

A microemulsion with Carthamus tinctorius extract effectively inhibits 5α-reductase and improves skin and hair follicle delivery.

Men with early balding showed higher levels of certain genes linked to hair loss and possibly prostate cancer.

Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.

Sphinganine can reduce hair loss and improve scalp health.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.

5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.

Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.

Two types of 5α-reductase are in dog skin, which might make dutasteride better than finasteride for treating dog hair loss.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Thujae occidentalis semen extract may help treat male pattern baldness by blocking a hair loss-related enzyme and reducing hair loss in mice.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

Dutasteride may help shrink prostate cancer tumors.

Finasteride improves hair growth in men with androgenetic alopecia.

DA-9401 helps protect rat testis from finasteride damage.

BB4CMU rice bran oil may help treat hair loss and gray hair.

Dutasteride may help treat prostate cancer by causing cancer cells to shrink and die.

Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

Finasteride exposure harms tadpole reproduction and hormone balance.

5α-reductase inhibitors can interfere with doping tests by masking banned substances.

Dutasteride more effective for hair growth, but has more side effects than finasteride.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

A new plant extract from Avicennia marina could potentially be used to treat common hair loss.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

The document concludes that combination therapy is most effective for treating excessive hair growth in women with idiopathic hirsutism, and more research is needed to understand the condition.

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.

Antiandrogen therapies are beneficial for treating skin and hair conditions related to androgen levels.

Dutasteride more effectively lowers DHT levels in men with enlarged prostates than finasteride.