5α-Reductase Inhibitors

    November 1997 in “ Andrology ”
    Roger S. Rittmaster
    Studysummary Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 14

    1. Outcome of Long-Term Treatment with the 5α-Reductase Inhibitor Finasteride in Idiopathic Hirsutism: Clinical and Hormonal Effects During a 1-Year Course of Therapy and 1-Year Follow-Up Fertility and Sterility · 1996
    2. The Efficacy of Terazosin, Finasteride, or Both in Benign Prostatic Hyperplasia The New England Journal of Medicine · 1996
    3. Effect of MK-386, a Novel Inhibitor of Type 1 5 Alpha-Reductase, Alone and in Combination with Finasteride, on Serum Dihydrotestosterone Concentrations in Men The Journal of Clinical Endocrinology and Metabolism · 1996
    4. Finasteride in the Treatment of Hirsutism: New Therapeutic Perspectives Fertility and Sterility · 1996
    5. Clinical and Endocrine Effects of Finasteride, a 5α-Reductase Inhibitor, in Women with Idiopathic Hirsutism Fertility and Sterility · 1995
    6. A Prospective Randomized Trial Comparing Finasteride to Spironolactone in the Treatment of Hirsute Women The Journal of Clinical Endocrinology and Metabolism · 1995
    7. Clinical and Hormonal Effects of the 5 Alpha-Reductase Inhibitor Finasteride in Idiopathic Hirsutism The Journal of Clinical Endocrinology and Metabolism · 1994
    8. The Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Scalp Skin Testosterone and Dihydrotestosterone Concentrations in Patients With Male Pattern Baldness The Journal of Clinical Endocrinology and Metabolism · 1994
    9. 5α-Reductase Inhibitors and Prostatic Disease Clinical endocrinology · 1994
    10. Finasteride The New England Journal of Medicine · 1994
    11. LY191704: A Selective, Nonsteroidal Inhibitor of Human Steroid 5 Alpha-Reductase Type 1 Proceedings of the National Academy of Sciences of the United States of America · 1993
    12. Prolonged Treatment with Finasteride (a 5α-Reductase Inhibitor) Does Not Affect Bone Density and Metabolism Clinical Endocrinology · 1992
    13. The Effect of Finasteride in Men with Benign Prostatic Hyperplasia The New England Journal of Medicine · 1992
    14. Effects of Finasteride (MK-906), a 5α-Reductase Inhibitor, on Circulating Androgens in Male Volunteers The Journal of Clinical Endocrinology and Metabolism · 1990