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Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

New compounds were made that effectively block a specific enzyme related to androgen conditions.

New compounds may soon be tested to treat excessive hair growth in women.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

Dutasteride may help reduce brain plaque linked to Alzheimer's by affecting cell energy structures and waste removal.

Researchers made two new compounds that could be used for medicine.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.

New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.

Four-amino acid part makes enzyme sensitive to finasteride.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

PPCM microspheres allow controlled finasteride release over 24 hours.

Researchers found new potential but less potent rat enzyme inhibitors using a 3D model.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

A new, simple, and accurate method was created to measure finasteride in tablets.

Finasteride safely lowers DHT levels without affecting testosterone.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.

Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.

New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

Validated method reliably measures finasteride in tablets using liquid chromatography.

Finasteride safely treats enlarged prostate and male-pattern baldness.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.