May 2026 in “Research Square” This research reports that the polyG fragment within the Hoxc13 protein alters its gene regulatory functions, which could have influenced mammalian hair evolution by affecting pathways related to hair follicle development.
This study reports that a novel ketoconazole-loaded microneedle array significantly enhances drug delivery and retention in the skin, demonstrating improved hair growth in animal models, suggesting a promising treatment for androgenic alopecia that addresses current topical therapies' limitations.
This study found a significant positive association between higher air quality index values and the incidence of alopecia areata, with a clear dose-response relationship observed among the participants.
In this open uncontrolled study on microneedling as an adjuvant therapy for frontal fibrosing alopecia, researchers observed stable frontotemporal recession measurements while patients reported improvements in quality of life and a reduction in inflammatory activity parameters.
This nested case-control study observed that patients with benign prostatic hyperplasia or androgenic alopecia who had a cumulative 5-ARI dose exceeding 5840 defined daily doses had a significantly reduced mortality risk, while lower doses were linked to higher mortality and suicide rates.
March 2024 in “Research Square (Research Square)” This study found no significant benefit of platelet-rich plasma injections over placebo in improving erectile function in patients with mild to moderate erectile dysfunction.
March 2024 in “Research Square (Research Square)” In this study, scalp cooling therapy was found to be well tolerated and effective at improving hair preservation for Asian women with breast or gynecological cancers undergoing certain chemotherapy regimens, particularly weekly paclitaxel, compared to historical controls.
February 2024 in “Research Square (Research Square)” In this study, researchers reported that both PRP and L-GF injections are effective in enhancing hair density and reducing recovery time post-transplantation in men with androgenetic alopecia, with L-GF showing slightly better but statistically insignificant results.
January 2024 in “Research Square (Research Square)” This study identified key genes related to ischemic stroke through the ferroptosis pathway and highlighted the potential role of specific traditional Chinese medicines in regulating associated biological processes.
January 2024 in “Research Square (Research Square)” This study identified robust susceptibility genes and potential drug candidates for male-pattern baldness, providing insights into the condition's molecular mechanisms.
December 2023 in “Research Square (Research Square)” This study observed that individuals with Down syndrome had a higher incidence of autoimmune skin conditions and a lower incidence of certain viral infections, indicating unique immune system dysregulation.
In this study, depression and anxiety were prevalent in Thai women with PCOS, with hirsutism being a key factor linked to these mental health issues, suggesting a need for targeted screening.
July 2023 in “Research Square (Research Square)” This study observed that a health coaching intervention for infertile women with PCOS significantly reduced waist circumference, increased physical activity, and improved lifestyle, although it did not significantly change BMI compared to routine care.
May 2023 in “Research Square (Research Square)” This study found that Muslim women who wear the hijab experienced an earlier onset of non-scarring alopecia compared to those who do not, with vitamin D deficiency and seborrheic dermatitis potentially contributing to the development of telogen effluvium in this group.
April 2023 in “Research Square (Research Square)” This study reported that 57% of healthcare workers experienced persistent post-COVID-19 complications, with common symptoms including hair loss, easy fatigability, mood swings, and anxiety.
January 2023 in “Research Square (Research Square)” In this study, a high prevalence of Demodex mites was observed among workers in the mining, textile, and food factory industries, with textile workers showing the highest rates, although differences between groups were not statistically significant.
January 2023 in “Research Square (Research Square)” This study found that patients with COVID-19 infection lasting longer than two weeks experienced more severe post-infection hair loss, with women and older individuals particularly affected.
November 2022 in “Research Square (Research Square)” This meta-analysis suggests a significant association between the use of facial sunscreen and moisturizer and frontal fibrosing alopecia, while finding no significant relationship with hair products or treatments.
This study found that wavy sinus hairs in cats were significantly associated with feline leukemia virus infection, suggesting this physical trait might be useful for identifying infected cats.
July 2022 in “Research Square (Research Square)” This study reports that Huaier promotes hair growth and tissue regeneration in cancer recovery by activating the Hedgehog signaling pathway, potentially preventing recurrence and metastasis independently from SMO function.
May 2022 in “Research Square (Research Square)” In this study, components like vitamin E, β-sitosterol, and linoleic acid in the kernel of Prunus mira Koehne were reported to promote hair growth in mice, possibly through the Wnt/β-catenin pathway.
April 2022 in “Research Square (Research Square)” In this case study, a rare scalp arteriovenous fistula developed after hair transplantation in a 29-year-old male was successfully treated using endovascular embolization with platinum coils, resulting in symptom resolution and complete fistula disappearance without complications.
February 2022 in “Research Square (Research Square)” This study concluded that an elevated serum Anti-Müllerian Hormone level is a strong predictor for diagnosing Polycystic Ovarian Syndrome among women of reproductive age with characteristic features of the condition.
January 2022 in “Research Square (Research Square)” This study determined that serum AMH levels are higher in women with PCOS compared to controls and may serve as a diagnostic marker for ovarian dysfunction alone or with other tools.
November 2021 in “Research Square (Research Square)” This study found that numerous long-term effects of SARS-CoV-2 were significantly associated with age and gender, while race, income, and education had limited significance.
November 2021 in “Research Square (Research Square)” This study optimized caffeine-loaded nanostructured lipid carriers for alopecia treatment, achieving enhanced skin permeation and promoting hair growth compared to a marketed formula, as shown through physiochemical evaluations and histological examination.
September 2021 in “Research Square (Research Square)” This study found that measuring specific steroid hormone levels can aid in diagnosing P450 oxidoreductase deficiency, a subtype of congenital adrenal hyperplasia, by distinguishing affected patients from healthy individuals.
June 2021 in “Research Square (Research Square)” This study found that non-small-cell lung cancer patients experienced less adverse events with third-generation EGFR-TKIs compared to first and second generations, although fear of cancer progression, anxiety, and depression were still prevalent.
February 2021 in “Research Square (Research Square)” In this observational study, the Liposome-Paclitaxel plus Carboplatin regimen showed better short-term efficacy and comparable long-term outcomes for serous ovarian cancer compared to other regimens.
January 2021 in “Research Square (Research Square)” This study found that STAT3 directly inhibits the sheep FST gene and cell proliferation, shedding light on the molecular mechanisms of hair follicle development and wool characteristics.