Prioritizing Susceptibility Genes for the Prognosis of Male-Pattern Baldness with Transcriptome-Wide Association Study

    January 2024 in “ Research Square (Research Square)
    Eun‐Young Choi, Jaeseung Song, Yubin Lee, Yun Hee Jeong, Wonhee Jang
    Image of study
    TLDR The research identified genes linked to male-pattern baldness and potential drug targets for treatment.
    The study "Prioritizing Susceptibility Genes for the Prognosis of Male-pattern Baldness with Transcriptome-wide Association Study" conducted an integrative analysis of gene expression and genotype data to identify susceptibility genes for male-pattern baldness (MPB). The researchers used tissue-specific enrichment analysis and single-tissue panels from genotype-tissue expression version 8, as well as cross-tissue panels from context-specific genetics. They identified 52, 75, and 144 MPB associations for type 2, type 3, and type 4 MPB respectively, and 10, 11, and 54 putative causality genes for the same types. The study also identified potential drug candidates connected to MPB-associated genes, which could help in developing treatments for MPB.
    Discuss this study in the Community →

    Research cited in this study

    29 / 29 results

    Related Community Posts Join

    6 / 1000+ results

    Similar Research

    5 / 1000+ results