research Prediction of male-pattern baldness from genotypes
This study found that a genetic model using SNPs can predict early-onset male-pattern baldness with moderate accuracy, which may assist in decisions about interventions.
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research Prioritizing Susceptibility Genes for the Prognosis of Male-pattern Baldness with Transcriptome-wide Association Study
This study identified robust susceptibility genes and potential drug candidates for male-pattern baldness, providing insights into the condition's molecular mechanisms.
research A population pharmacokinetic model for individualized regimens of finasteride according to CYP3A5 genotype and liver function
In this study, researchers found that among healthy Korean males, the clearance of finasteride was about 34% lower in individuals with the CYP3A5*3 homozygous allele compared to other genotypes, suggesting dosage adjustments may be necessary considering CYP3A5 and ALT levels to avoid adverse effects.
research Genotype-phenotype correlation in boys with X-linked hypohidrotic ectodermal dysplasia
The study reported a significant genotype–phenotype correlation in prepubescent males with XLHED, particularly in the severity of skin and hair manifestations between those with different EDA mutations.
research Application of big data analytics in minoxidil drug development: a data-driven model for predicting efficacy and side effect risks
This study found that a data-driven model using XGBoost effectively predicts individualized responses to minoxidil for androgenetic alopecia, outperforming traditional methods in accuracy and reliability.
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5 / 6 resultscommunity Could male-pattern baldness have a secondary photobiological function? The Solar Window Hypothesis
Male-pattern baldness might increase UVB exposure on the scalp, potentially affecting vitamin D and skeletal health. The hypothesis is debated, with some seeing it as a minor benefit in specific contexts.
community I don’t think my hair loss is caused by DHT – quitting finasteride after 3 months (1 mg). Need opinions
The user plans to stop finasteride after three months, believing hair loss isn't due to DHT, and will continue with oral minoxidil, microneedling, and ketoconazole shampoo. They suspect stress and poor nutrition are the main causes and seek opinions on DHT blockers' effectiveness.
community Minoxidil works only with Retinoic acid
Minoxidil is more effective when combined with retinoic acid, such as tretinoin or tazarotene, enhancing hair growth. Some users experience significant regrowth, while others see minimal effects or side effects.
community 30-Min Dermatology Visit – Best Questions to Ask About Balding? ( 175$ )
The conversation discusses hair loss treatments, focusing on finasteride, minoxidil, and other options like PRP and ketoconazole. It highlights the importance of asking specific questions during a dermatology visit to determine the cause of hair loss and appropriate treatments.
community Why do so many people trash on finasteride?
Finasteride is effective for hair regrowth, especially on the crown, but can cause side effects like reduced libido and erectile dysfunction in some users. Opinions are mixed, with some reporting positive results without side effects and others experiencing significant issues.
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