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Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Future research should focus on making bioengineered skin that completely restores all skin functions.

Bioengineered salivary glands in mice can produce saliva when tasting sour or bitter, but have different protein levels and nerve signals compared to natural glands.

New materials help control stem cell growth and specialization for medical applications.

The pituitary gland functions normally even after losing most SOX2+ stem cells.

Bioinspired polymers are promising for advanced medical treatments and tissue repair.

Photothermal hydrogels are promising for infection control and tissue repair, and combining them with other treatments could improve results and lower costs.

Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.

New scaffold materials help heal severe skin wounds and improve skin regeneration.

Chitosan hydrogels are promising for repairing blood vessels but need improvements in strength and compatibility.

Microneedle technology has improved drug delivery and patient comfort but needs more research for broader use.

Nanoparticles added to natural materials like cellulose and collagen can improve cell growth and wound healing, but more testing is needed to ensure they're safe and effective.

Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.

Exosomes show promise for future tissue regeneration.

The new nanocomposite films are stronger, protect against UV, speed up wound healing, and are antibacterial without being toxic.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

Single-cell engineered biotherapeutics show promise for skin treatment but need more research and trials.

MSCs and their exosomes may speed up skin wound healing but need more research for consistent use.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

Polyurethane dressings show promise for wound healing but need improvements to adapt better to the healing process.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.

Electrospun scaffolds can improve healing in diabetic wounds.

Special gels help heal diabetic foot sores and reduce the risk of amputation or death.

Different types of facial fat affect aging and treatment outcomes; more research is needed to enhance anti-aging procedures.

Smart biomaterials that guide tissue repair are key for future medical treatments.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.