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Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

Hair loss drugs like finasteride may cause lasting sexual and mood side effects, and more research is needed to understand these risks.

Finasteride may increase depression by reducing brain cell growth.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Consider benefits and risks of new alopecia treatments for safety.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Wnt3a activates certain genes in hair follicle cells, including a newly discovered one, EP2, which may affect hair growth.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Finasteride blocks deoxycorticosterone's anticonvulsant effects in infant rats, but indomethacin doesn't.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Finasteride may cause slight depression and anxiety.

Testosterone improves mood and thinking skills; finasteride has no effect.

Finasteride might affect memory by impacting cholinergic system.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

DHT in the human prostate is produced through multiple pathways, not just from testosterone.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

A new method accurately measures nine specific hormones in human blood.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Finasteride reduces new brain cells in male mice, possibly causing depression.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

A brain-produced steroid causes increased scratching in mice with a skin condition similar to eczema.