An Old Problem with a New Cause: 5 Alpha Reductase Inhibitors and Persistent Sexual Dysfunction

    July 2011 in “ The Journal of Sexual Medicine ”
    Irwin Goldstein
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    TLDR Hair loss drugs like finasteride may cause lasting sexual and mood side effects, and more research is needed to understand these risks.
    The editorial from 2011 discussed the persistent sexual, cognitive, and mood-related side effects caused by 5 alpha reductase inhibitors like finasteride and dutasteride, which are used for treating hair loss and urinary symptoms. It stressed the importance of better informed consent about these potential side effects, noting that patients often feel misled due to insufficient warnings from healthcare providers. The lack of research into these side effects, particularly studies not funded by pharmaceutical companies or the government, was highlighted, along with a call for more investigation to understand the risks and help those affected. The International Society of Hair Restoration Surgery recognized the need for further research to establish a clear causal link and identify individuals at risk. The editorial concluded with an emphasis on the role of sexual medicine specialists in preventing drug-induced sexual dysfunction and the necessity for more research in the area.
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      community Trying to understand finasteride side effects and post finasteride syndrome

      in Finasteride/Dutasteride  74 upvotes 4 years ago
      The conversation discusses the side effects of finasteride, including low libido and erectile dysfunction, and the possibility of these effects being permanent, known as post-finasteride syndrome (PFS). Some users report personal experiences with PFS and debate whether the condition is real, with varying opinions on the reversibility of side effects and the role of individual biology.

      community Is this broscience? From More Plates, More Dates

      in Research/Science  22 upvotes 8 months ago
      The conversation discusses whether finasteride's reduction of DHT and increase in scalp testosterone contribute to hair follicle miniaturization. Some participants argue testosterone does not cause miniaturization, while others suggest that even with reduced DHT, other androgens like testosterone may still contribute to hair loss.

      community I talked to urologist about Finasteride and just wanted to share what he said

      in Finasteride  235 upvotes 6 years ago
      The effects of Finasteride, a drug used to treat hair loss, prostate problems and other conditions. The post by iaskedadoctor describes the conversations they had with a Urologist about the effects of the drug on DHT levels throughout the body, how lower doses are beneficial in reducing side effects, how erectile dysfunction can be psychological as well as physiological, how morning erections are not necessarily important, and how persistent side effects appear to be rare. People also shared their experiences with taking Finasteride for hair loss, including potential side effects such as reduced ejaculate force and development of man boobs.

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