An Old Problem with a New Cause: 5 Alpha Reductase Inhibitors and Persistent Sexual Dysfunction

    July 2011 in “ The Journal of Sexual Medicine ”
    Irwin Goldstein
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    TLDR Hair loss drugs like finasteride may cause lasting sexual and mood side effects, and more research is needed to understand these risks.
    The editorial from 2011 discussed the persistent sexual, cognitive, and mood-related side effects caused by 5 alpha reductase inhibitors like finasteride and dutasteride, which are used for treating hair loss and urinary symptoms. It stressed the importance of better informed consent about these potential side effects, noting that patients often feel misled due to insufficient warnings from healthcare providers. The lack of research into these side effects, particularly studies not funded by pharmaceutical companies or the government, was highlighted, along with a call for more investigation to understand the risks and help those affected. The International Society of Hair Restoration Surgery recognized the need for further research to establish a clear causal link and identify individuals at risk. The editorial concluded with an emphasis on the role of sexual medicine specialists in preventing drug-induced sexual dysfunction and the necessity for more research in the area.
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