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Glossary Persistent Sexual Dysfunction

long-lasting sexual issues after stopping certain medications

Persistent Sexual Dysfunction refers to long-lasting sexual problems that continue even after stopping a medication or treatment that initially caused them. This can include issues like reduced libido, erectile dysfunction, or difficulty achieving orgasm. It is often associated with certain medications, such as antidepressants or finasteride, which is used for hair loss treatment.

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Research

5 / 1000+ results

research Persistent Sexual Dysfunction and Suicidal Ideation in Young Men Treated with Low-Dose Finasteride: A Pharmacovigilance Study

69 citations , July 2015 in “Pharmacotherapy”

This study found that low-dose finasteride use in young men was associated with higher reporting of persistent sexual dysfunction, with some cases linked to suicidal ideation.

research Persistent Sexual Dysfunction with Finasteride 1 mg Taken for Hair Loss

19 citations , September 2016 in “Pharmacotherapy”

This study found that the risk of persistent sexual dysfunction was higher in men who stopped using finasteride 1 mg compared to omeprazole users.

research Persistent sexual dysfunction and depression in finasteride users for male pattern hair loss: a serious concern or red herring?

10 citations , December 2014 in “PubMed”

This review examines reports of prolonged sexual dysfunction and depression associated with finasteride for male pattern hair loss, concluding that significant biases exist and further rigorous trials are needed to assess risks.

research An Old Problem with a New Cause-5 Alpha Reductase Inhibitors and Persistent Sexual Dysfunction

9 citations , July 2011 in “The Journal of Sexual Medicine”

This article examines 5 alpha-reductase inhibitors and their link to persistent sexual dysfunction, but it reports no new clinical findings.

research PROSPECTIVE EVALUATION ON SEXUAL DYSFUNCTION PERSISTENCE, WORSENING OR IMPROVEMENT IN BPH PATIENTS AFTER FINASTERIDE OR DUTASTERIDE TREATMENT

March 2008 in “European Urology Supplements”

Finasteride and dutasteride can affect sexual function in BPH patients.

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Community Join

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community Publication concludes finasteride is a associated with a 60% risk of persistent sexual dysfunction.

345 upvotes 6 months ago

Finasteride is not linked to a 60% risk of persistent sexual dysfunction; this figure applies only to those already experiencing sexual issues. Most users do not have side effects, and the study's methodology is criticized for selection bias.

community Androsterone as a Neurosteroid Replacement Strategy for 5α-Reductase Inhibitor–Associated Sexual and Affective Dysfunction

in Research/Science 36 upvotes 2 months ago

Androsterone may help with sexual and affective dysfunction from finasteride by replacing disrupted neurosteroids without increasing androgenic side effects. Controlled testing is needed to confirm its effectiveness and safety.

community Finasteride does deplete important nuero-active steroids

11 upvotes 3 years ago

Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.

community Sexual Sides? Are you sure you don't masturbate too much?

13 upvotes 9 years ago

Finasteride can cause sexual side effects, and reducing porn and masturbation may help improve sexual function. Some users experience persistent issues even after stopping finasteride.

community PSA: Most men who stay on Fin will see the sexual side effects go away. Stop the fear mongering

192 upvotes 4 years ago

Finasteride can cause sexual side effects in less than 2% of men, but these often disappear over time, even if the treatment continues. Some users report persistent side effects, while others experience no issues or only temporary ones.

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Learn

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learn Overview

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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