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    Did you mean 5-alpha-reductase inhibitor?
    Glossary 5-alpha-reductase inhibitor

    blocks enzyme converting testosterone to dihydrotestosterone (DHT)

    A 5-alpha-reductase inhibitor is a type of medication that blocks the enzyme 5-alpha-reductase, which is responsible for converting testosterone into dihydrotestosterone (DHT). By reducing DHT levels, these inhibitors can help treat conditions like male pattern baldness and benign prostatic hyperplasia (BPH).

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    Research 10 of 1000+

    1. 5-Alpha Reductase Inhibitors and Erectile Dysfunction: The Connection The Journal of Sexual Medicine · 2008 · 78 citations
    2. Effects of 5-alpha reductase inhibitors on erectile function, sexual desire and ejaculation Expert Opinion on Drug Safety · 2012 · 71 citations
    3. Effects of finasteride, a type 2 5-alpha reductase inhibitor, on fetal development in the rhesus monkey (Macaca mulatta) Teratology · 1997 · 67 citations
    4. The effect of finasteride, a 5 alpha-reductase inhibitor, on scalp skin testosterone and dihydrotestosterone concentrations in patients with male pattern baldness. The Journal of Clinical Endocrinology and Metabolism · 1994 · 59 citations
    5. 5 Alpha-reductase inhibitors: whatʼs new? Current opinion in urology · 2003 · 47 citations
    6. 5‐alpha‐reductase inhibitors are associated with reduced frequency of COVID‐19 symptoms in males with androgenetic alopecia Journal of The European Academy of Dermatology and Venereology · 2020 · 36 citations
    7. A Review of the FAERS Data on 5-Alpha Reductase Inhibitors: Implications for Postfinasteride Syndrome Urology · 2018 · 35 citations
    8. Side Effects of 5‐Alpha Reductase Inhibitors: A Comprehensive Review Sexual medicine reviews · 2013 · 35 citations
    9. Hair growth effects of oral administration of finasteride, a steroid 5 alpha-reductase inhibitor, alone and in combination with topical minoxidil in the balding stumptail macaque. The Journal of Clinical Endocrinology and Metabolism · 1992 · 34 citations
    10. Investigation of the Plausibility of 5-Alpha-Reductase Inhibitor Syndrome Skin appendage disorders · 2016 · 33 citations
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    Community 10 of 1000+

    1. BREAKTHROUGH: I’m a radiochemist and discovered a radioactive isotope scalp serum that OUTPERFORMS Minoxidil and 5-AR inhibitors! (Lab Data Inside) Reddit · 10 Jun 2025
    2. Why does this industry still revolve around 5-AR inhibitors? Reddit · 14 Jun 2021
    3. [Discussion] Trichoscopy in sudden-onset AGA: Pathology and reversibility of "Yellow Dots" without 5AR-inhibitors? Reddit · 22 Mar 2026
    4. Guys if you can’t take 5AR inhibitors still get on treatment ASAP Reddit · 6 Jan 2026
    5. 1 year 5-ar. Blood test results Reddit · 29 Jul 2025
    6. Meta analysis of minoxidil only vs 5AR inhibitors Reddit · 16 May 2025
    7. Can gains from stemoxydine be permanently kept with 5AR inhibitors? Reddit · 29 Dec 2024
    8. FINALLY stopped shedding constantly after 1 year on 5ar inhibitors!! Moral of the story: Just wait Reddit · 15 Oct 2024
    9. Allopregnanolone deficiency by 5-ari inhibition (fin/dut users) Reddit · 11 Dec 2023
    10. 4 months on oral dutasteride + one month and 3 weeks on topical minoxidil 5% Reddit · 23 May 2026
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    Learn 6 of 24

    1. Dutasteride 5-alpha reductase inhibitor that blocks both enzyme types, a stronger DHT blocker than finasteride
    2. Finasteride Popular 5-alpha reductase inhibitor that lowers DHT, taken as a pill or used topically
    3. Neem Oil Oil from the neem tree, used in traditional remedies
    4. Saw Palmetto Palm-berry extract taken as a supplement
    5. Azelaic Acid Acid used in acne and rosacea creams
    6. Rosemary Herb whose oil is used in hair care
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