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The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

Letrozole reduces seizures but not brain damage in mice.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.

PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

Neurosteroids show promise for treating epilepsy and more research is needed.

Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.

Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.

People with hidradenitis suppurativa are more likely to have bipolar disorder than those with psoriasis or without skin conditions.

Patients with certain skin diseases are willing to spend significant time on treatment, indicating a high impact on their lives and a need for better treatments.

Hidradenitis suppurativa may be related to hormones and patients often have metabolic disorders; more research is needed to understand this connection.

Different treatments for Hidradenitis suppurativa range from antibiotics and hormonal therapies to surgery, depending on severity.

Immune cells in Hidradenitis suppurativa become more inflammatory and may be important for treatment targets.

Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.

People with certain skin conditions, especially androgenic alopecia, are more likely to have metabolic syndrome.

Laser treatment and deroofing are effective options for hidradenitis suppurativa.

Hidradenitis Suppurativa is likely an autoinflammatory disease, and better understanding its causes could improve treatments.

Young HS patients often have other physical and mental health issues, and research on HS covers a wide range of topics including genetics, triggers, treatments, and the need for more data.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

Acitretin significantly reduced inflammatory attacks in a woman with Naevus Comedonicus Syndrome but caused side effects.

Hormones might affect the skin condition hidradenitis suppurativa, but their exact role is unclear.

The research confirms that Hidradenitis Suppurativa is characterized by increased inflammation, disrupted skin cell organization, and abnormal metabolic processes.

Hidradenitis suppurativa might be a type of autoinflammatory skin disease.