Growth Hormone and the Human Hair Follicle

    December 2021 in “ International journal of molecular sciences ”
    Elijah J. Horesh, Jérémy Chéret, Ralf Paus
    Studysummary This article reviews current knowledge and research gaps on growth hormone in hair follicle biology, highlighting its complex role and suggesting further exploration to reveal nonclassical skin functions.
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    Research cited in this study 29

    1. The biology of human hair greying Biological reviews/Biological reviews of the Cambridge Philosophical Society · 2020
    2. Growth Hormone Operates as a Neuroendocrine Regulator of Human Hair Growth Ex Vivo ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2019
    3. Olfactory Receptor OR2AT4 Regulates Human Hair Growth Nature Communications · 2018
    4. Eccrine Sweat Glands Associate With the Human Hair Follicle Within a Defined Compartment of Dermal White Adipose Tissue British Journal of Dermatology · 2018
    5. Further Clinical Evidence for the Effect of IGF-1 on Hair Growth and Alopecia Skin appendage disorders · 2017
    6. The Thyroid Hormone Analogue KB2115 (Eprotirome) Prolongs Human Hair Growth (Anagen) Ex Vivo Journal of Investigative Dermatology · 2016
    7. Both Low Circulating Insulin-Like Growth Factor-1 and High-Density Lipoprotein Cholesterol Are Associated with Hair Loss in Middle-Aged Women British Journal of Dermatology · 2016
    8. Severe Scalp Hair Loss in a Female Patient with Acromegaly Treated with Lanreotide Autogel After Unsuccessful Surgery Clinical Case Reports · 2015
    9. Human Hair Follicle Organ Culture: Theory, Application, and Perspectives Experimental Dermatology · 2015
    10. Thyroxine Differentially Modulates the Peripheral Clock: Lessons from the Human Hair Follicle PLoS ONE · 2015
    11. The Peripheral Clock Regulates Human Pigmentation ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2014
    12. Neuroendocrinology of the Hair Follicle: Principles and Clinical Perspectives Trends in Molecular Medicine · 2014
    13. Differential Effects of Caffeine on Hair Shaft Elongation, Matrix and Outer Root Sheath Keratinocyte Proliferation, and Transforming Growth Factor-β2/Insulin-Like Growth Factor-1-Mediated Regulation of the Hair Cycle in Male and Female Human Hair Follicles In Vitro British Journal of Dermatology · 2014
    14. Insulin-Like Growth Factor-1: Roles in Androgenetic Alopecia Experimental Dermatology · 2014
    15. A Meeting of Two Chronobiological Systems: Circadian Proteins Period1 and BMAL1 Modulate the Human Hair Cycle Clock Journal of Investigative Dermatology · 2013
    16. Hypothalamic–Pituitary–Thyroid Axis Hormones Stimulate Mitochondrial Function and Biogenesis in Human Hair Follicles Journal of Investigative Dermatology · 2013
    17. Tumor Necrosis Factor Alpha, Interferon Gamma, and Substance P Are Novel Modulators of Extrapituitary Prolactin Expression in Human Skin PLOS ONE · 2013
    18. Scalp Hair Loss After Transsphenoidal Adenomectomy in Patients With Acromegaly Clinical Endocrinology · 2012
    19. Safety and Efficacy Analysis of Liposomal Insulin-Like Growth Factor-1 in a Fluid Gel Formulation for Hair-Loss Treatment in a Hamster Model Clinical and Experimental Dermatology · 2012
    20. Endocannabinoids Limit Excessive Mast Cell Maturation And Activation In Human Skin Journal of Allergy and Clinical Immunology · 2012
    21. Effect of IGF-I on Hair Growth Is Related to the Anti-Apoptotic Effect of IGF-I and Up-Regulation of PDGF-A and PDGF-B Annals of Dermatology · 2012
    22. Thyrotropin-Releasing Hormone and Estrogen Differentially Regulate Prolactin and Prolactin Receptor Expression in Female Human Skin and Hair Follicles In Vitro British Journal of Dermatology · 2010
    23. Thyroid-Stimulating Hormone: A Novel, Locally Produced Modulator of Human Epidermal Functions, Regulated by Thyrotropin-Releasing Hormone and Thyroid Hormones Endocrinology · 2010
    24. Mind the Gender Gap: Does Prolactin Exert Gender and Site-Specific Effects on the Human Hair Follicle? Journal of Investigative Dermatology · 2009
    25. Thyrotropin Releasing Hormone: A New Player in Human Hair Growth Control ˜The œFASEB journal · 2009
    26. Human Female Hair Follicles Are a Direct, Nonclassical Target for Thyroid-Stimulating Hormone Journal of Investigative Dermatology · 2008
    27. Thyroid Hormones Directly Alter Human Hair Follicle Functions: Anagen Prolongation and Stimulation of Both Hair Matrix Keratinocyte Proliferation and Hair Pigmentation The Journal of Clinical Endocrinology & Metabolism · 2008
    28. Human Scalp Hair Follicles Are Both a Target and a Source of Prolactin, Which Serves as an Autocrine and/or Paracrine Promoter of Apoptosis-Driven Hair Follicle Regression American Journal of Pathology · 2006
    29. Human Hair Follicles Display a Functional Equivalent of the Hypothalamic-Pituitary-Adrenal (HPA) Axis and Synthesize Cortisol The FASEB Journal · 2005

    Related research 7

    1. Role of Low Dose Oral Minoxidil in the Treatment of Hair Loss: A Review Cosmoderma · 2021
    2. Protection Against Chemotherapy-Induced Alopecia: Targeting ATP-Binding Cassette Transporters in the Hair Follicle Trends in pharmacological sciences · 2013
    3. Pathobiology of Chemotherapy-Induced Hair Loss The Lancet Oncology · 2013
    4. TrichoScan: A Novel Tool for the Analysis of Hair Growth In Vivo Journal of Investigative Dermatology Symposium Proceedings · 2003
    5. Towards a Molecular Understanding of Hair Loss and Its Treatment Trends in Molecular Medicine · 2001
    6. Drug-Induced Hair Loss and Hair Growth Drug Safety · 1994
    7. Disorders of Hair Growth: Diagnosis and Treatment McGraw-Hill eBooks · 1994