Taurine-Based Active Pharmaceutical Ingredient Ionic Liquids Modulate the Perifollicular Microenvironment for Androgenic Alopecia Treatment

    June 2026 in “ Advanced Healthcare Materials ”
    Lianyi Yang, Yazhen Wang, Lei Lei … Jun Cao
    Studysummary In this study, a taurine-based ionic liquid was developed to effectively penetrate the skin barrier and deliver antioxidants to hair follicles, reducing oxidative stress and promoting hair regrowth in an androgenic alopecia animal model.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on doi.org →
    Discuss this study in the Community →

    Research cited in this study 17

    1. Androgenetic Alopecia Nature Reviews Disease Primers · 2025
    2. The Skin Microenvironment: A Dynamic Regulator of Hair Follicle Development, Cycling, and Disease Biomolecules · 2025
    3. Association of Male Androgenetic Alopecia with Psychosocial and Sexual Well-being in Early Middle-aged Men: A Northern Finland Birth Cohort 1986 Study Acta Dermato Venereologica · 2025
    4. Single-Nucleus and Bulk RNA Sequencing Reveals the Involvement of Natural Killer and CD8+ T Cells in the Progression of Androgenetic Alopecia Journal of Inflammation Research · 2025
    5. Immune and Non-Immune Interactions in the Pathogenesis of Androgenetic Alopecia Clinical Reviews in Allergy & Immunology · 2025
    6. Epidemiological Landscape of Androgenetic Alopecia in the US: An All of Us Cross-Sectional Study PLoS ONE · 2025
    7. Transdermal Delivery of Valproate–Choline Ionic Liquid Induces Hair Regrowth ACS Applied Materials & Interfaces · 2025
    8. Hair Follicles Modulate Skin Barrier Function Cell Reports · 2024
    9. Oxidative Stress in Hair Follicle Development and Hair Growth: Signaling Pathways, Intervening Mechanisms and Potential of Natural Antioxidants Journal of Cellular and Molecular Medicine · 2024
    10. Multifunctional Ionic Liquids-Mediated Topical Delivery of Minoxidil and EGCG for Treating Androgenic Alopecia Through Promoting Angiogenesis and Scavenging ROS Chemical engineering journal · 2024
    11. Androgenetic Alopecia: Therapy Update Drugs · 2023
    12. The Psychological Consequences of Androgenetic Alopecia: A Systematic Review Journal of Cosmetic Dermatology · 2022
    13. Perifollicular Inflammation and Follicular Spongiosis in Androgenetic Alopecia Journal of The American Academy of Dermatology · 2021
    14. Recreation of a Hair Follicle Regenerative Microenvironment: Successes and Pitfalls Bioengineering & translational medicine · 2021
    15. Dihydrotestosterone-Induced Hair Regrowth Inhibition by Activating Androgen Receptor in C57BL6 Mice Simulates Androgenetic Alopecia Biomedicine & Pharmacotherapy · 2021
    16. Pediatric Androgenetic Alopecia: A Review Journal of The American Academy of Dermatology · 2019
    17. Androgens and Androgen Receptor Action in Skin and Hair Follicles Molecular and Cellular Endocrinology · 2017