A Multi-Omic Single-Cell Landscape of Perinatal Mouse Skin Maps Lineage Specification and Reveals Shared Dynamics in Human Fetal Skin
April 2026
in “
Experimental & Molecular Medicine
”
Studysummary This study used integrated single-cell chromatin and transcriptomic analyses in developing mouse skin to uncover gene networks involved in skin lineage specification and identified Mef2c+ upper fibroblasts as potential precursors to certain muscle-like structures, with cross-species findings in human skin.
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