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    Glossary Chromatin Accessibility

    degree to which DNA is exposed for cellular processes

    Chromatin accessibility refers to how easily DNA can be reached and read by cellular machinery. In simple terms, it's like how open a book is: if the pages are tightly closed, it's hard to read, but if they're open, it's easy. For professionals, it indicates the degree to which chromatin structure allows transcription factors and other proteins to interact with DNA, influencing gene expression and cellular function.

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    1. DNA dioxygenases Tet2/3 regulate gene promoter accessibility and chromatin topology in lineage-specific loci to control epithelial differentiation Science advances · 2023 · 3 citations
    2. TTNPB Promotes Human Pluripotent Stem Cell‐to‐Neural Stem Cell Transition via Modulation of Chromatin Accessibility and the S‐(5′‐adenosyl)‐L‐homocysteine/Choline Metabolic Network Advanced Science · 2026
    3. 1440 DNA dioxygenases Tet2/3 regulate gene promoter accessibility and chromatin topology in lineage-specific loci to control keratinocyte differentiation and hair growth 2023
    4. 723 DNA dioxygenases Tet2/3 regulate gene promoter accessibility and three-dimensional chromatin topology in lineage-specific loci to control hair growth 2022
    5. States and Fates of Skin Fibroblasts Revealed through Chromatin Accessibility Journal of Investigative Dermatology · 2022
    6. Profiling Chromatin Accessibility at Single-Cell Resolution Genomics Proteomics & Bioinformatics · 2021 · 52 citations
    7. Single-cell chromatin landscapes of mouse skin development Scientific Data · 2022 · 2 citations
    8. Deciphering a Message from the Nucleus: How Transcription Factors and Spatial Chromatin Interactions Orchestrate Epidermal Differentiation 2023
    9. 766 H3K9me3 methyltransferase SETDB1 controls retrotransposon silencing, DNA methylation, constitutive heterochromatin maintenance and 3D-chromatin structure in epidermal keratinocytes 2023
    10. AP-1 and TGFß cooperativity drives non-canonical Hedgehog signaling in resistant basal cell carcinoma Nature Communications · 2020 · 60 citations
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