An Integrative Analysis of the LncRNA-MiRNA-mRNA Competitive Endogenous RNA Network Reveals Potential Mechanisms in the Murine Hair Follicle Cycle

October 2022 in “ Frontiers in Genetics ”

Yuxin Ding, Yuhong Chen, Xiaoshuang Yang, Piaopiao Xu, Jing Jing, Yu-Jie Miao, Meiqi Mao, Jiali Xu, Xianjie Wu, Lu Zhang

lncRNA miRNA mRNA competitive endogenous RNA ceRNA hair follicle cycle anagen phase telogen phase GSPT1 gene androgenetic alopecia alopecia hair growth signaling pathways hair growth hair loss hair cycle growth phase rest phase

Studysummary This study found that miRNAs increase and target mRNAs and lncRNAs decrease from the anagen to telogen phase in mouse hair follicles, and these ceRNA networks may play a role in hair follicle cycling.

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