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GlossaryLong Non-Coding RNAs (lncRNAs)

regulate gene expression without coding for proteins

Long Non-Coding RNAs (lncRNAs) are a type of RNA molecule that are longer than 200 nucleotides and do not code for proteins. Instead, they play crucial roles in regulating gene expression, influencing processes such as cell differentiation, development, and disease mechanisms, including those related to hair growth and alopecia.

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research Genome-Wide Detection and Sequence Conservation Analysis of Long Non-Coding RNA During Hair Follicle Cycle of Yak

March 2020 in “Research Square (Research Square)”

Different long non-coding RNAs in yaks change during hair growth cycles and are involved in key growth pathways.

research Effects of LncRNA MTC on Protein Expression in Skin Fibroblasts of Liaoning Cashmere Goat Based on iTRAQ Technique

3 citations , September 2022 in “Animal biotechnology”

lncRNA MTC affects protein levels in goat skin cells, impacting hair growth.

research Lnc056 Enhances Hair Follicle Stem Cells Proliferation by Binding Transcription Factor HNRNPUL1 to Up-Regulate TRIP6 Expression

June 2025 in “PubMed”

Lnc056 helps hair follicle stem cells grow by increasing TRIP6 expression.

research Application of LncRNA-miRNA-mRNA CeRNA Network Analysis in the Treatment of Androgenic Alopecia

1 citations , December 2022 in “PubMed”

The lncRNA LOXL1-AS1 may help diagnose and treat androgenic alopecia.

research Analysis of LncRNA-mRNA Co-Expression Profiles in Patients With Polycystic Ovary Syndrome: A Pilot Study

4 citations , April 2021 in “Frontiers in Immunology”

Different types of RNAs are found in varying amounts in patients with Polycystic Ovary Syndrome, suggesting they could be important in the disease's development and potentially used as disease markers.

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