16 citations
,
June 2019 in “International Journal of Women's Dermatology” This study found that type 2 diabetes was associated with a higher risk of severe central scalp hair loss in African American women.
12 citations
,
January 2019 in “International Journal of Trichology” This study found that trichoscopy revealed significant differences in certain variables, such as the brown peripilar sign and white peripilar sign, which may aid in diagnosing early and late stages of androgenetic alopecia.
66 citations
,
June 2018 in “International Journal of Women's Dermatology” This article discusses treatments for female pattern hair loss, highlighting that oral antiandrogens and topical minoxidil can effectively arrest progression and reverse miniaturization in many patients with mild-to-moderate cases, but it reports no new clinical results.
3 citations
,
April 2018 in “Cosmetics” This study found that females with androgenic alopecia experienced greater improvements in hair density after cosmetic treatments compared to males, in a cohort stratified by age and gender.
13 citations
,
February 2018 in “Dermatologic Therapy” This study found that 65.2% of female pattern hair loss patients showed significant hair growth improvement with a daily dosage of 2.5 mg finasteride, with better outcomes in patients with lower initial Ludwig scores and older age at onset.
3 citations
,
January 2018 in “International Journal of Trichology” The authors concluded that their new grading system can effectively classify early female pattern hair loss and evaluate treatment progress.
7 citations
,
January 2018 in “International Journal of Trichology” Taking 5 mg/day finasteride can cause side effects in women with hair loss, but these are usually mild and fade over time, making the treatment beneficial in the long run.
80 citations
,
December 2017 in “International Journal of Dermatology” This study reported that once-daily treatment with oral minoxidil and spironolactone for 12 months reduced hair loss severity and hair shedding in women with pattern hair loss, with generally mild side effects, though results came from an uncontrolled, observational pilot study.
53 citations
,
June 2017 in “Skin appendage disorders” This review suggests that platelet-rich plasma may be effective in increasing hair density in patients with androgenetic alopecia, but more research is needed to determine the best treatment protocol.
21 citations
,
February 2017 in “International Journal of Women's Dermatology” This review discusses the physiology and potential hormonal mechanisms involved in female pattern hair loss, as well as the current hormonal and hormone-modifying treatments available, but reports no new research findings.
48 citations
,
January 2017 in “International Journal of Trichology” This study found that combining microneedling with PRP and topical minoxidil (5%) significantly improved hair growth in men with androgenetic alopecia compared to using minoxidil alone.
36 citations
,
December 2016 in “Journal of The American Academy of Dermatology” In this study, researchers evaluated the hair pull test and found that normal values should be reduced to two hairs or fewer, with no significant impact from hair washing, brushing, or lifestyle factors such as hair texture and medication use.
26 citations
,
December 2015 in “Journal of The European Academy of Dermatology and Venereology” This article introduces a new grading system called the FPHL Severity Index to better identify and monitor early stages of female pattern hair loss using clinical criteria.
8 citations
,
October 2015 in “PubMed” Recent Phase III trials reported that once daily 5% minoxidil foam significantly increased hair count in women with female pattern hair loss and was shown to be as effective as twice daily 2% minoxidil solution.
91 citations
,
August 2015 in “Anais Brasileiros De Dermatologia” This review discusses the clinical, epidemiological, and pathophysiological aspects of female pattern hair loss, reporting no new research findings.
69 citations
,
January 2015 in “Current problems in dermatology” This review discusses trichoscopy as a noninvasive, effective technique for diagnosing various hair loss conditions and monitoring treatment, highlighting its potential to reduce scalp biopsy necessity.
151 citations
,
May 2014 in “American Journal of Clinical Dermatology” This review concluded that oral finasteride for men and topical minoxidil for both genders have the most evidence supporting their effectiveness and safety for treating androgenetic alopecia.
160 citations
,
April 2014 in “Drug discovery today” This review discusses the mechanism of action of melatonin in various disorders and suggests its potential for designing new receptor ligands, but reports no new clinical findings.
35 citations
,
January 2014 in “BioMed Research International” This review examines the epidemiology, pathogenesis, clinical manifestations, and diagnosis of female pattern hair loss and reports no new results.
26 citations
,
December 2013 in “Aesthetic Plastic Surgery” In this study, micropigmentation was reported to be an effective method for camouflaging hair loss and scalp scars in Korean patients, with high satisfaction in 42 out of 43 cases.
57 citations
,
October 2013 in “international journal of endocrinology and metabolism” This review discusses clinical features, differential diagnosis, and treatments for female pattern hair loss, emphasizing the use of 2% topical Minoxidil and exploring alternative off-label therapies.
42 citations
,
August 2013 in “International Journal of Women's Health” This review discusses the current therapeutic options for female pattern hair loss and emphasizes the need for managing patient expectations of permanent regrowth, reporting no new clinical results.
37 citations
,
April 2013 in “Plastic and Reconstructive Surgery” This study found that environmental factors such as smoking, alcohol consumption, exercise, and testosterone levels may significantly influence various forms of hair loss in male identical twins.
48 citations
,
April 2013 in “Expert Opinion on Investigational Drugs” This article reviews emerging treatments for androgenetic alopecia, including topical 5-alpha-reductase inhibitors and prostaglandin modulators, but reports no clinical results and calls for further efficacy evidence, especially for PRP.
21 citations
,
November 2012 in “Plastic and Reconstructive Surgery” The researchers reported that various environmental factors and higher testosterone levels were linked to different patterns of hair loss in women with androgenic alopecia.
46 citations
,
October 2012 in “Dermatologic Clinics” This review discusses treatment options for female pattern hair loss, emphasizing the importance of early intervention and the benefits of combined therapies, but reports no new clinical results.
87 citations
,
May 2012 in “PLOS Genetics” This study found that early-onset androgenetic alopecia in individuals of European ancestry is significantly associated with increased odds of Parkinson's disease and is influenced by specific genetic loci, including some linked to reduced fertility.
9 citations
,
May 2012 in “British Journal of Dermatology” This article discusses female androgenetic alopecia but reports no new clinical findings.
205 citations
,
March 2012 in “Science Translational Medicine” PGD2 stops hair growth and is higher in bald men with AGA.
40 citations
,
February 2012 in “Dermatology Online Journal” This review discusses cases and research on paradoxical hair growth after laser hair removal and explores laser and light therapies for treating alopecia, but reports no new results.
19 citations
,
January 2012 in “Dermato-endocrinology” This study suggests that moderate elevated prolactin levels are unlikely to cause significant hair loss in women, but still warrant further diagnostic investigation to rule out a prolactin-producing pituitary tumor.
39 citations
,
January 2012 in “International Journal of Trichology” This study found that topical melatonin solution was associated with positive effects on hair density and reduction in hair loss for androgenetic alopecia, with good tolerability reported in several clinical trials.
45 citations
,
January 2012 in “International Journal of Trichology” This study reported that trichoscopy is a more effective diagnostic tool than the trichogram for early diagnosis of FAGA, regardless of hair shaft diversity cut-off levels.
50 citations
,
October 2011 in “Archives of Biochemistry and Biophysics” This study found that while calcium can substitute for the Vitamin D receptor in maintaining epidermal keratinocyte differentiation, it cannot compensate for hair follicle dysfunction caused by the absence of the receptor.
198 citations
,
October 2011 in “Journal der Deutschen Dermatologischen Gesellschaft” This article discusses the development of an evidence-based guideline for treating androgenetic alopecia and reports no new research results.
47 citations
,
August 2011 in “Journal of The European Academy of Dermatology and Venereology” This study found that treatment with a 1550 nm fractional erbium–glass laser increased hair density and thickness in women with female pattern hair loss, suggesting it may be an effective and safe option.
100 citations
,
June 2011 in “Journal of The American Academy of Dermatology” This study found that a once-daily 5% minoxidil topical foam is as effective as a twice-daily 2% minoxidil topical solution for hair growth in women with androgenetic alopecia, with fewer side effects and greater styling convenience.
18 citations
,
March 2011 in “Journal of The American Academy of Dermatology” Familial factors affect hair loss types in Koreans, with M type in men, L type in women, and paternal factors influencing male hair loss more.
151 citations
,
August 2010 in “British Journal of Dermatology” This guideline reviews the diagnosis of androgenetic alopecia and offers expert consensus recommendations tailored to males, females, and adolescents, but reports no new clinical results.
129 citations
,
January 2009 in “International Journal of Trichology” This study found that trichoscopy criteria can distinguish female androgenic alopecia from chronic telogen effluvium, with specific features achieving 98% diagnostic specificity.
26 citations
,
January 2007 in “Organogenesis” This review outlines the evolution of hair follicle engineering and its foundational discoveries, but reports no new experimental results.
50 citations
,
January 2007 in “PubMed” This review discusses female pattern hair loss, highlighting that while oral antiandrogens and topical minoxidil can arrest progression, early diagnosis and treatment are crucial, and stresses the need for ongoing therapy.
215 citations
,
November 2006 in “Journal of The American Academy of Dermatology” This study found that dutasteride increased scalp hair growth in men with male pattern hair loss, particularly at a 2.5 mg dose, and was more effective than finasteride over 24 weeks.
28 citations
,
August 2006 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified that survivin is expressed in human hair follicles during their growth phase and its expression may be regulated by Wnt/β-catenin signaling, potentially influencing the balance between cell proliferation and apoptosis in hair follicle cycles.
100 citations
,
June 2006 in “British Journal of Dermatology” This study found that as hair loss severity increased in women with female pattern hair loss, the number of vellus follicles also rose, indicating miniaturization of terminal hair follicles.
63 citations
,
October 2005 in “Archives of Dermatology” This study reports that a hair shedding threshold of 100 hairs or more may provide the best concordance with clinical diagnosis for distinguishing chronic telogen effluvium from androgenetic alopecia.
179 citations
,
March 2005 in “British Journal of Dermatology” This study found that 88% of women with female pattern hair loss who received oral antiandrogens saw no progression or improvement in their condition.
208 citations
,
December 2003 in “Journal of Investigative Dermatology” This study found that dermal papilla and peribulbar dermal sheath cup cells in mice can both induce hair follicle formation, suggesting they may have similar functional roles in hair growth.
86 citations
,
February 2003 in “Journal of The American Academy of Dermatology” This article discusses various mechanisms for promoting hair growth in pattern hair loss and highlights the challenge of balancing short-term measurable results in trials with the need for long-term efficacy data.
92 citations
,
October 2002 in “Journal of The American Academy of Dermatology” This study reports that oral finasteride improved or stabilized hair loss in women with hyperandrogenism but not in postmenopausal women with female pattern hair loss.
226 citations
,
September 2001 in “Journal of The American Academy of Dermatology” Hair loss in women is genetic, diagnosed by examination and biopsy, and treated with minoxidil, finasteride, or transplantation.
236 citations
,
July 2001 in “Trends in Molecular Medicine” This review discusses common hair loss conditions and explores how advancements in hair follicle biology might lead to more effective treatments but reports no new results.
157 citations
,
July 2001 in “British Journal of Dermatology” In this study, the prevalence of androgenetic alopecia among Korean men and women was found to be lower than in caucasians, with Korean men showing more frontal hairline preservation and a higher incidence of 'female pattern' hair thinning.
239 citations
,
November 2000 in “Journal of The American Academy of Dermatology” In this study, finasteride 1 mg/day for 12 months did not improve hair growth or slow hair thinning in postmenopausal women with androgenetic alopecia compared to placebo.
131 citations
,
August 2000 in “International Journal of Dermatology” Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.
1113 citations
,
August 1999 in “The New England Journal of Medicine” This article discusses the biologic and psychosocial significance of hair, the current limitations in hair growth drugs, and anticipates future therapies based on advancing hair follicle research.
92 citations
,
January 1998 in “Dermatology” This study found that 2% ketoconazole shampoo improved hair density and anagen follicle proportion in androgenic alopecia similarly to minoxidil treatment, suggesting a potential role for Malassezia in inflammation.
2 citations
,
January 1989 in “PubMed” In this study, 48% of women with androgenetic alopecia showed hypothyroidism or hyperprolactinemia after TRH stimulation, suggesting these conditions may influence androgen metabolism and contribute to hair loss.
666 citations
,
September 1977 in “British Journal of Dermatology” This article presents a classification system for stages of female-pattern androgenetic alopecia to aid early diagnosis and mentions existing systems for rare male-pattern cases, but reports no new clinical results.
