Alopecia Areata: An Update on Treatment Options for Children

The document reviewed treatment options for children with alopecia areata, including topical and systemic corticosteroids, topical immunotherapy, and newer options like JAK inhibitors. Clobetasol propionate and diphencyprone were effective, while high-dose pulse corticosteroid therapy had high relapse rates. JAK inhibitors, especially tofacitinib, showed promise with significant hair regrowth in studies involving up to 90 patients. Oral tofacitinib showed transient efficacy in adolescents with alopecia universalis, and topical ruxolitinib was explored for potential benefits. Methotrexate, alone or with corticosteroids, was effective in severe cases. The document emphasized individualized treatment plans and the need for further research on long-term safety and efficacy in children.