Methotrexate in Severe Childhood Alopecia Areata: Long-Term Follow-Up

June 2015 in “ Acta dermato-venereologica ”

P. Lucas, Christine Bodemer, S. Barbarot, P. Vabres, Mathieu Royer, J. Mazereeuw‐Hautier

methotrexate alopecia areata hair regrowth

TLDR Methotrexate can help some kids with severe hair loss regrow hair.

The document discussed the long-term follow-up of using methotrexate in treating severe childhood alopecia areata. The study indicated that methotrexate could be an effective treatment option for this condition, providing sustained hair regrowth in some pediatric patients. However, the document did not provide specific details on the number of participants or the exact outcomes, making it difficult to assess the overall strength and generalizability of the findings.

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Research cited in this study

2 / 2 results

research Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition

701 citations, August 2014 in “Nature medicine”

Alopecia areata can be reversed by JAK inhibitors, promoting hair regrowth.

research Efficacy and Tolerability of Methotrexate in Severe Childhood Alopecia Areata

70 citations, April 2011 in “British journal of dermatology/British journal of dermatology, Supplement”

Methotrexate sometimes helps regrow hair in children with severe alopecia areata and is generally safe.

Related Research

1 / 1 results

research Twenty Nail Dystrophy with Alopecia Areata in an Atopic Child

April 2019 in “International journal of research in dermatology”

A child with rough nails also had hair loss and allergies.