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    Effect of Physical Stimuli on Hair Follicle Deposition of Clobetasol-Loaded Lipid Nanocarriers

    January 2020 in “ Scientific Reports
    Tamara Ângelo, Nesma El‐Sayed, Marijas Jurisic … Taís Gratieri
    Studysummary This study found that nanostructured lipid carriers with clobetasol propionate significantly enhance follicular drug delivery compared to commercial cream, and manual massage further doubles follicular retention.
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    Research cited in this study 20

    1. Solid Effervescent Formulations as a New Approach for Topical Minoxidil Delivery European Journal of Pharmaceutical Sciences · 2016
    2. Chromatographic Method for Clobetasol Propionate Determination in Hair Follicles and Different Skin Layers Biomedical Chromatography · 2016
    3. Nanocarriers for Optimizing the Balance Between Interfollicular Permeation and Follicular Uptake of Topically Applied Clobetasol to Minimize Adverse Effects Journal of Controlled Release · 2015
    4. Triggered Release of Model Drug from Gold Nanoparticle-Doped Bovine Serum Albumin Nanocarriers in Hair Follicles Using Infrared A Radiation Acta Biomaterialia · 2015
    5. Human Hair Follicle Organ Culture: Theory, Application, and Perspectives Experimental Dermatology · 2015
    6. Applications and Limitations of Lipid Nanoparticles in Dermal and Transdermal Drug Delivery via the Follicular Route European journal of pharmaceutics and biopharmaceutics · 2015
    7. Chitosan Nanoparticles for Targeting and Sustaining Minoxidil Sulphate Delivery to Hair Follicles International Journal of Biological Macromolecules · 2015
    8. Quantification of Nanoparticle Uptake Into Hair Follicles in Pig Ear and Human Forearm Journal of Controlled Release · 2014
    9. Influence of Massage and Occlusion on the Ex Vivo Skin Penetration of Rigid Liposomes and Invasomes European journal of pharmaceutics and biopharmaceutics · 2013
    10. Long-Term Removal of Unwanted Hair Using Light Dermatologic clinics · 2012
    11. Penetration of Drugs Through Skin: A Complex Rate-Controlling Membrane 2012
    12. Human Hair Follicle: Reservoir Function and Selective Targeting British Journal of Dermatology · 2011
    13. Effects of the Lexington LaserComb on Hair Regrowth in the C3H/HeJ Mouse Model of Alopecia Areata Lasers in Medical Science · 2011
    14. Selective Follicular Targeting by Modification of the Particle Sizes Journal of Controlled Release · 2011
    15. Methods for Quantifying Intrafollicular Drug Delivery: A Critical Appraisal Expert Opinion on Drug Delivery · 2010
    16. Heat Treatment Increases the Incidence of Alopecia Areata in the C3H/HeJ Mouse Model Cell Stress and Chaperones · 2010
    17. Efficacy And Safety Of A New Clobetasol Propionate 0.05% Foam In Alopecia Areata: A Randomized, Double-Blind Placebo-Controlled Trial Journal of the European Academy of Dermatology and Venereology · 2006
    18. Transfollicular Drug Delivery: Is It a Reality? International journal of pharmaceutics · 2005
    19. Clobetasol Propionate 0.05% Under Occlusion in the Treatment of Alopecia Totalis/Universalis Journal of the American Academy of Dermatology · 2003
    20. Human Hair Growth In Vitro Journal of Cell Science · 1990

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