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research Effect of physical stimuli on hair follicle deposition of clobetasol-loaded Lipid Nanocarriers

52 citations , January 2020 in “Scientific Reports”

This study found that nanostructured lipid carriers with clobetasol propionate significantly enhance follicular drug delivery compared to commercial cream, and manual massage further doubles follicular retention.

research Surgical Pearl: Mechanoanesthesia to reduce the pain of local injections

13 citations , April 2001 in “Journal of The American Academy of Dermatology”

Using a vibrating device during injections can help reduce pain.

research Hair resistance to mechanical wear

3 citations , January 2021 in “Wear”

This study presents a new method for evaluating cosmetic treatments by measuring the resistance of hair to mechanical wear, revealing differences related to hair ethnicity and treatment type.

research Structure of the sinus hair follicle in the big‐clawed shrew, Sorex unguiculatus

46 citations , August 1977 in “Journal of Morphology”

This study examined the unique structural features of sinus hair follicles in the shrew Sorex unguiculatus, which suggest a specialization for vibration sensing.

research Sensations Evoked by Microstimulation of Single Mechanoreceptive Afferents Innervating the Human Face and Mouth

63 citations , February 2010 in “Journal of Neurophysiology”

This study observed that electrical stimulation of specific mechanoreceptive afferents in the orofacial region can evoke sensations consistent with their response properties, while others may require multiple afferents to access perceptual levels.

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community Story time! The Great Unbalding (PP405)

230 upvotes 11 months ago

PP405 is a promising new hair loss treatment that may reactivate dormant hair follicles without side effects. It could surpass traditional treatments like minoxidil and finasteride if successful in further trials.

community Hair loss research focused on chemistry for decades because we misunderstood the mechanics of growth.

51 upvotes 7 months ago

Hair growth relies on mechanical forces, not just chemicals, with tissue acting like a motor. Minoxidil and finasteride help, but maintaining tissue elasticity and addressing mechanical issues are essential.

community How to deal with mechanically induced shedding

4 upvotes 11 months ago

Minoxidil can cause scalp dryness and flaking, leading to hair shedding when exfoliating. Alternatives like oral Minoxidil, finasteride, and ketoconazole shampoo are suggested to manage these issues.

community Funny Encounter With a Mechanic - Hair Loss Update

in Update 39 upvotes 5 months ago

The user has been taking 3.75mg of finasteride weekly for 8 months, which has improved their hairline and hair texture. They shared a humorous encounter with a bald mechanic who complimented their hair, unaware of the finasteride use.

community Hi-c5 protein, explains why the mechanical tension theory may be correct.

22 upvotes 1 month ago

Hair loss may be influenced by mechanical tension and inflammation, with the hi-c5 protein amplifying androgen effects, leading to follicle miniaturization. Treatments like finasteride, minoxidil, and scalp massages are suggested to manage hair loss.

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